Richard A. and Susan F. Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, MA (A.N.K., J.X., Y.S., R.W.Y., R.K.W.).
Harvard Medical School, Boston, MA (A.N.K.).
Circulation. 2022 Jul 19;146(3):211-228. doi: 10.1161/CIRCULATIONAHA.122.060199. Epub 2022 Jul 18.
Black adults experience a disproportionately higher burden of cardiovascular risk factors and disease in comparison with White adults in the United States. Less is known about how sex-based disparities in cardiovascular mortality between these groups have changed on a national scale over the past 20 years, particularly across geographic determinants of health and residential racial segregation.
We used CDC WONDER (Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research) to identify Black and White adults age ≥25 years in the United States from 1999 to 2019. We calculated annual age-adjusted cardiovascular mortality rates (per 100 000) for Black and White women and men, as well as absolute rate differences and rate ratios to compare the mortality gap between these groups. We also examined patterns by US census region, rural versus urban residence, and degree of neighborhood segregation.
From 1999 to 2019, age-adjusted mortality rates declined overall for both Black and White adults. There was a decline in age-adjusted cardiovascular mortality among Black (602.1 to 351.8 per 100 000 population) and White women (447.0 to 267.5), and the absolute rate difference (ARD) between these groups decreased over time (1999: ARD, 155.1 [95% CI, 149.9-160.3]; 2019: ARD, 84.3 [95% CI, 81.2-87.4]). These patterns were similar for Black (824.1 to 526.3 per 100 000) and White men (637.5 to 396.0; 1999: ARD, 186.6 [95% CI, 178.6-194.6]; 2019: ARD, 130.3 [95% CI, 125.6-135.0]). Despite this progress, cardiovascular mortality in 2019 was higher for Black women (rate ratio, 1.32 [95% CI, 1.30-1.33])- especially in the younger (age <65 years) subgroup (rate ratio, 2.28 [95% CI, 2.23-2.32])-as well as for Black men (rate ratio, 1.33 [95% CI, 1.32-1.34]), compared with their respective White counterparts. There was regional variation in cardiovascular mortality patterns, and the Black-White gap differed across rural and urban areas. Cardiovascular mortality rates among Black women and men were consistently higher in communities with high levels of racial segregation compared with those with low to moderate levels.
During the past 2 decades, age-adjusted cardiovascular mortality declined significantly for Black and White adults in the United States, as did the absolute difference in death rates between these groups. Despite this progress, Black women and men continue to experience higher cardiovascular mortality rates than their White counterparts.
与美国的白人成年人相比,黑人成年人面临着不成比例的更高心血管风险因素和疾病负担。关于这两个群体之间的心血管死亡率性别差异在过去 20 年中如何在全国范围内发生变化,特别是在健康的地理决定因素和居住的种族隔离方面,人们知之甚少。
我们使用 CDC WONDER(疾病控制与预防中心的广泛在线数据用于流行病学研究)在美国确定了 1999 年至 2019 年期间年龄≥25 岁的黑人和白人成年人。我们计算了每 100000 名黑人和白人女性和男性的年度年龄调整心血管死亡率(每 100000 人),以及绝对死亡率差异和死亡率比值,以比较这些群体之间的死亡率差距。我们还检查了按美国人口普查区域、城乡居住和邻里隔离程度划分的模式。
从 1999 年到 2019 年,黑人和白人成年人的年龄调整死亡率总体都有所下降。黑人(从每 100000 人 602.1 降至 351.8)和白人女性(从每 100000 人 447.0 降至 267.5)的年龄调整心血管死亡率都有所下降,并且这两个群体之间的绝对死亡率差异(ARD)随着时间的推移而减少(1999 年:ARD,155.1 [95% CI,149.9-160.3];2019 年:ARD,84.3 [95% CI,81.2-87.4])。黑人(从每 100000 人 824.1 降至 526.3)和白人男性(从每 100000 人 637.5 降至 396.0)也呈现出类似的模式(1999 年:ARD,186.6 [95% CI,178.6-194.6];2019 年:ARD,130.3 [95% CI,125.6-135.0])。尽管取得了这些进展,但 2019 年黑人女性(死亡率比值,1.32 [95% CI,1.30-1.33])的心血管死亡率仍然更高,尤其是在年龄较小(<65 岁)的亚组中(死亡率比值,2.28 [95% CI,2.23-2.32]),以及黑人男性(死亡率比值,1.33 [95% CI,1.32-1.34]),与各自的白人同龄人相比。心血管死亡率模式存在地区差异,农村和城市地区之间的黑人和白人差距也不同。与低至中等水平种族隔离的社区相比,黑人女性和男性的心血管死亡率在种族隔离程度较高的社区中始终较高。
在过去的 20 年里,美国黑人和白人成年人的年龄调整心血管死亡率显著下降,这两个群体之间的死亡率差异也有所缩小。尽管取得了这一进展,但黑人女性和男性的心血管死亡率仍高于白人。