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主要大都市区内经导管主动脉瓣置换术获取机会的种族、民族和社会经济差异。

Racial, Ethnic, and Socioeconomic Disparities in Access to Transcatheter Aortic Valve Replacement Within Major Metropolitan Areas.

机构信息

Division of Cardiology, Hospital of the University of Pennsylvania, Philadelphia.

Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, University of Pennsylvania, Philadelphia.

出版信息

JAMA Cardiol. 2022 Feb 1;7(2):150-157. doi: 10.1001/jamacardio.2021.4641.

Abstract

IMPORTANCE

Despite the benefits of high-technology therapeutics, inequitable access to these technologies may generate disparities in care.

OBJECTIVE

To examine the association between zip code-level racial, ethnic, and socioeconomic composition and rates of transcatheter aortic valve replacement (TAVR) among Medicare patients living within large metropolitan areas with TAVR programs.

DESIGN, SETTING, AND PARTICIPANTS: This multicenter, nationwide cross-sectional analysis of Medicare claims data between January 1, 2012, and December 31, 2018, included beneficiaries of fee-for-service Medicare who were 66 years or older living in the 25 largest metropolitan core-based statistical areas.

EXPOSURE

Receipt of TAVR.

MAIN OUTCOMES AND MEASURES

The association between zip code-level racial, ethnic, and socioeconomic composition and rates of TAVR per 100 000 Medicare beneficiaries.

RESULTS

Within the studied metropolitan areas, there were 7590 individual zip codes. The mean (SD) age of Medicare beneficiaries within these areas was 71.4 (2.0) years, a mean (SD) of 47.6% (5.8%) of beneficiaries were men, and a mean (SD) of 4.0% (7.0%) were Asian, 11.1% (18.9%) were Black, 8.0% (12.9%) were Hispanic, and 73.8% (24.9%) were White. The mean number of TAVRs per 100 000 Medicare beneficiaries by zip code was 249 (IQR, 0-429). For each $1000 decrease in median household income, the number of TAVR procedures performed per 100 000 Medicare beneficiaries was 0.2% (95% CI, 0.1%-0.4%) lower (P = .002). For each 1% increase in the proportion of patients who were dually eligible for Medicaid services, the number of TAVR procedures performed per 100 000 Medicare beneficiaries was 2.1% (95% CI, 1.3%-2.9%) lower (P < .001). For each 1-unit increase in the Distressed Communities Index score, the number of TAVR procedures performed per 100 000 Medicare beneficiaries was 0.4% (95% CI, 0.2%-0.5%) lower (P < .001). Rates of TAVR were lower in zip codes with higher proportions of patients of Black race and Hispanic ethnicity, despite adjusting for socioeconomic markers, age, and clinical comorbidities.

CONCLUSIONS AND RELEVANCE

Within major metropolitan areas in the US with TAVR programs, zip codes with higher proportions of Black and Hispanic patients and those with greater socioeconomic disadvantages had lower rates of TAVR, adjusting for age and clinical comorbidities. Whether this reflects a different burden of symptomatic aortic stenosis by race and socioeconomic status or disparities in use of TAVR requires further study.

摘要

重要性

尽管高科技疗法有其益处,但获得这些技术的机会不平等可能会导致护理方面的差异。

目的

研究大型都市区内邮政编码级别的种族、民族和社会经济构成与接受经导管主动脉瓣置换术(TAVR)的 Medicare 患者比例之间的关系,这些都市区都开展了 TAVR 项目。

设计、地点和参与者:这是一项多中心、全国性的 Medicare 索赔数据的横断面分析,纳入了 2012 年 1 月 1 日至 2018 年 12 月 31 日期间,居住在有 TAVR 项目的 25 个最大的都市区核心统计区的年龄在 66 岁或以上的,接受费用报销型 Medicare 的受益人的数据。

暴露

接受 TAVR。

主要结果和测量指标

邮政编码级别的种族、民族和社会经济构成与 Medicare 受益人的 TAVR 率(每 10 万 Medicare 受益人数)之间的关联。

结果

在所研究的大都市地区,有 7590 个个人邮政编码。这些地区的 Medicare 受益人的平均(标准差)年龄为 71.4(2.0)岁,平均(标准差)47.6%(5.8%)的受益人为男性,平均(标准差)4.0%(7.0%)为亚洲人,11.1%(18.9%)为黑人,8.0%(12.9%)为西班牙裔,73.8%(24.9%)为白人。每个邮政编码的 TAVR 中位数为 249(IQR,0-429)。中位数家庭收入每降低 1000 美元,每 100000 Medicare 受益人的 TAVR 手术数量就会降低 0.2%(95%CI,0.1%-0.4%)(P=0.002)。每增加 1%符合 Medicaid 服务双重资格的患者比例,每 100000 Medicare 受益人的 TAVR 手术数量就会降低 2.1%(95%CI,1.3%-2.9%)(P<0.001)。每增加 1 个 Distressed Communities Index 得分,每 100000 Medicare 受益人的 TAVR 手术数量就会降低 0.4%(95%CI,0.2%-0.5%)(P<0.001)。尽管调整了社会经济指标、年龄和临床合并症,但黑人种族和西班牙裔患者比例较高的邮政编码的 TAVR 率较低。

结论和相关性

在美国开展 TAVR 项目的主要都市区内,黑人患者和西班牙裔患者比例较高且社会经济劣势较大的邮政编码的 TAVR 率较低,这一结果在考虑了年龄和临床合并症后依然成立。这是否反映了不同种族和社会经济地位的症状性主动脉瓣狭窄的负担不同,或者是否反映了 TAVR 使用方面的差异,需要进一步研究。

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