Lan Jun, Zhang HuaYan, Sheng RuDan, He YuanJun
Department of Rheumatology and Nephrology, Zhejiang quhua hospital, Quzhou City, Zhejiang Province, China.
Scott Med J. 2022 Nov;67(4):144-156. doi: 10.1177/00369330221112175. Epub 2022 Jul 21.
Hip fractures are a commonly occurring comorbidity in patients with chronic kidney disease. To evaluate the comparative rates of post-operative complications, revision surgery, and mortality after hip fracture surgery in chronic kidney disease patients undergoing hemodialysis.
A systematic search of the academic literature was performed according to the PRISMA guidelines across five databases: Web of Science, EMBASE, CENTRAL, Scopus, and MEDLINE. A random-effect meta-analysis was conducted to evaluate the overall comparative risks of post-operative complications in chronic kidney disease patients.
Out of 993 studies, 11 eligible studies were included in the review, with a total of 72618 chronic kidney disease patients (mean age: 75.3 ± 3.0 years), and 50566 healthy controls (75.3 ± 2.6 years). Meta-analysis revealed a higher risk of post-operative complications (Odd's ratio: 1.76), revision surgeries (1.69), and mortality-related outcomes (2.47) after hip fracture surgery in chronic kidney disease patients undergoing hemodialysis as compared to chronic kidney disease patients not undergoing hemodialysis.
We report higher risks of post-operative complications, revision surgery, and mortality in chronic kidney disease patients undergoing hemodialysis as compared to chronic kidney disease patients not undergoing hemodialysis.
髋部骨折是慢性肾脏病患者常见的合并症。旨在评估接受血液透析的慢性肾脏病患者髋部骨折手术后的术后并发症、翻修手术及死亡率的比较发生率。
根据PRISMA指南，在五个数据库（科学网、EMBASE、CENTRAL、Scopus和MEDLINE）中对学术文献进行系统检索。进行随机效应荟萃分析，以评估慢性肾脏病患者术后并发症的总体比较风险。
在993项研究中，11项符合条件的研究纳入本综述，共纳入72618例慢性肾脏病患者（平均年龄：75.3 ± 3.0岁）和50566例健康对照者（75.3 ± 2.6岁）。荟萃分析显示，与未接受血液透析的慢性肾脏病患者相比，接受血液透析的慢性肾脏病患者髋部骨折手术后出现术后并发症（优势比：1.76）、翻修手术（1.69）及死亡相关结局（2.47）的风险更高。
我们报告，与未接受血液透析的慢性肾脏病患者相比，接受血液透析的慢性肾脏病患者术后并发症、翻修手术及死亡的风险更高。
