• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

维持性血液透析患者髋部骨质疏松性骨折的手术治疗与保守治疗:一项回顾性分析

Surgical vs. conservative treatment for hip osteoporotic fracture in maintenance hemodialysis patients: a retrospective analysis.

作者信息

Zhang Man-Yu, Song Wei, Wang Jing-Bo, Lv Rui-Qian, Zhao Fu-Hao, Yang Ding-Wei

机构信息

Department of Nephrology, Tianjin Hospital of Tianjin University, Tianjin, China.

Department of Hip Traumatology, Tianjin Hospital of Tianjin University, Tianjin, China.

出版信息

Front Surg. 2024 Dec 6;11:1471101. doi: 10.3389/fsurg.2024.1471101. eCollection 2024.

DOI:10.3389/fsurg.2024.1471101
PMID:39713805
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11659257/
Abstract

BACKGROUND

HSip Osteoporotic fractures are common complications with high mortality in patients undergoing maintenance hemodialysis (MHD). It remains unclear whether surgical or conservative should be adopted for hip fractures in MHD patients.

METHODS

A retrospective analysis was conducted in Tianjin Hospital of Tianjin University from August 2019 to August 2023. A total of 43 MHD patients with hip fracture were included, with 30 cases in the surgical group and 13 cases in the conservative group. The differences in cumulative survival rates, time to first ambulation, Harris score, Barthel index, and incidence of complications were compared.

RESULTS

The surgical group had remarkable lower mortality rates as compared with the conservative group at 1, 2, 3, 6, 12, 24 months (13.33 VS. 38.46%, 26.67 VS. 53.85%, 26.67 VS. 53.85%, 26.67 VS. 61.54%, 26.67 VS. 61.54%, and 26.67 VS. 69.23%). In the surgical treatment group, the first ambulation time was reduced to 28 (26) days, which was superior to the conservative group (134.17 ± 43.18 days,  < 0.001). The Harris score at 1 month (61.50 ± 4.10) and the Barthel index at 3 months (95, 11.25) were also significantly higher ( < 0.001). Furthermore, the surgical group had a significantly lower overall incidence of complications (60.00 vs. 92.31%,  = 0.034). The risk of death and complications of surgical treatment was only 23.0 and 32.4% of conservative treatment in MHD patients with hip fracture.

CONCLUSION

Surgical treatment is effective and safe and should be the first choice for hip fracture in MHD patients.

摘要

背景

髋部骨质疏松性骨折是维持性血液透析(MHD)患者常见的并发症,死亡率较高。对于MHD患者的髋部骨折应采用手术治疗还是保守治疗仍不明确。

方法

对天津医科大学天津医院2019年8月至2023年8月期间进行回顾性分析。共纳入43例MHD髋部骨折患者,手术组30例,保守组13例。比较两组累积生存率、首次下地行走时间、Harris评分、Barthel指数及并发症发生率的差异。

结果

手术组在1、2、3、6、12、24个月时的死亡率显著低于保守组(13.33%对38.46%,26.67%对53.85%,26.67%对53.85%,26.67%对61.54%,26.67%对61.54%,26.67%对69.23%)。手术治疗组首次下地行走时间缩短至28(26)天,优于保守组(134.17±43.18天,P<0.001)。1个月时的Harris评分(61.50±4.10)和3个月时的Barthel指数(95,11.25)也显著更高(P<0.001)。此外,手术组并发症总发生率显著更低(60.00%对92.31%,P=0.034)。MHD髋部骨折患者手术治疗的死亡和并发症风险仅为保守治疗的23.0%和32.4%。

结论

手术治疗有效且安全,应作为MHD患者髋部骨折的首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/51127073745d/fsurg-11-1471101-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/202a8d384d2b/fsurg-11-1471101-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/a5d4a4a1b143/fsurg-11-1471101-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/51127073745d/fsurg-11-1471101-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/202a8d384d2b/fsurg-11-1471101-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/a5d4a4a1b143/fsurg-11-1471101-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e0/11659257/51127073745d/fsurg-11-1471101-g003.jpg

相似文献

1
Surgical vs. conservative treatment for hip osteoporotic fracture in maintenance hemodialysis patients: a retrospective analysis.维持性血液透析患者髋部骨质疏松性骨折的手术治疗与保守治疗:一项回顾性分析
Front Surg. 2024 Dec 6;11:1471101. doi: 10.3389/fsurg.2024.1471101. eCollection 2024.
2
Excess Mortality for Femoral Intertrochanteric Fracture Patients Aged 50 Years and Older Treated Surgically and Conservatively in Tianjin, China: A Cohort Study.天津市 50 岁及以上股骨转子间骨折手术和非手术治疗患者的超额死亡率:一项队列研究。
Orthop Surg. 2024 Jan;16(1):207-215. doi: 10.1111/os.13925. Epub 2023 Nov 17.
3
Mortality and complications after hip fracture among elderly patients undergoing hemodialysis.接受血液透析的老年患者髋部骨折后的死亡率和并发症
BMC Nephrol. 2015 Jul 7;16:100. doi: 10.1186/s12882-015-0099-0.
4
Prospective assessment of key factors influencing treatment strategy and outcome of fragility fractures of the pelvis (FFP).前瞻性评估影响骨盆脆性骨折(FFP)治疗策略和结果的关键因素。
Eur J Trauma Emerg Surg. 2022 Aug;48(4):3243-3256. doi: 10.1007/s00068-022-01887-1. Epub 2022 Feb 5.
5
Effects of Zoledronic Acid Treatment on Fracture Healing, Morbidity and Mortality in Elderly Patients with Osteoporotic Hip Fractures.唑来膦酸治疗对老年骨质疏松性髋部骨折患者骨折愈合、发病率及死亡率的影响
Strategies Trauma Limb Reconstr. 2019 Sep-Dec;14(3):126-131. doi: 10.5005/jp-journals-10080-1439.
6
Risk factors associated with 1-year mortality after osteoporotic hip fracture in Hawai'i: higher mortality risk among Native Hawaiians and other Pacific Islanders.夏威夷骨质疏松性髋部骨折后 1 年死亡率的相关风险因素:夏威夷原住民和其他太平洋岛民的死亡率风险更高。
Osteoporos Int. 2024 Nov;35(11):1931-1941. doi: 10.1007/s00198-024-07195-1. Epub 2024 Jul 30.
7
Zoledronic acid for hip fracture during initial hospitalization.唑来膦酸治疗初始住院期间的髋部骨折。
J Bone Miner Res. 2024 Aug 21;39(8):1061-1070. doi: 10.1093/jbmr/zjae101.
8
Percutaneous vertebroplasty for treatment of painful osteoporotic vertebral compression fractures: an evidence-based analysis.经皮椎体成形术治疗疼痛性骨质疏松性椎体压缩骨折:一项循证分析
Ont Health Technol Assess Ser. 2010;10(19):1-45. Epub 2010 Oct 1.
9
Prognostic Implications of Preoperative Pneumonia for Geriatric Patients Undergoing Hip Fracture Surgery or Arthroplasty.术前肺炎对老年髋部骨折手术或关节置换患者的预后影响。
Orthop Surg. 2020 Dec;12(6):1890-1899. doi: 10.1111/os.12830. Epub 2020 Oct 28.
10
Low bone density and high morbidity in patients between 55 and 70 years with displaced femoral neck fractures: a case-control study of 50 patients vs 150 normal controls.55-70 岁移位股骨颈骨折患者的低骨密度和高发病率:50 例患者与 150 例正常对照的病例对照研究。
BMC Musculoskelet Disord. 2019 Aug 14;20(1):371. doi: 10.1186/s12891-019-2732-8.

引用本文的文献

1
A nomogram for one-year risk of death after hip fracture.髋部骨折后一年死亡风险的列线图。
Front Med (Lausanne). 2025 May 30;12:1500049. doi: 10.3389/fmed.2025.1500049. eCollection 2025.

本文引用的文献

1
Epidemiological analysis of death among patients on maintenance hemodialysis: results from the beijing blood purification quality Control and Improvement Center.维持性血液透析患者死亡的流行病学分析:来自北京血液净化质量控制和改进中心的结果。
BMC Nephrol. 2023 Aug 15;24(1):236. doi: 10.1186/s12882-023-03271-6.
2
Magnesium and Fracture Risk in the General Population and Patients Receiving Dialysis: A Narrative Review.普通人群及接受透析治疗患者中的镁与骨折风险:一项叙述性综述
Can J Kidney Health Dis. 2023 Feb 17;10:20543581231154183. doi: 10.1177/20543581231154183. eCollection 2023.
3
The impact of chronic kidney disease and dialysis therapy on outcomes of elderly patients with hip fractures: A systematic review and meta-analysis.
慢性肾脏病及透析治疗对老年髋部骨折患者预后的影响:一项系统评价与荟萃分析
Scott Med J. 2022 Nov;67(4):144-156. doi: 10.1177/00369330221112175. Epub 2022 Jul 21.
4
Serum Osteoprotegerin Level Is Negatively Associated with Bone Mineral Density in Patients Undergoing Maintenance Hemodialysis.维持性血液透析患者的血清护骨素水平与骨密度呈负相关。
Medicina (Kaunas). 2021 Jul 27;57(8):762. doi: 10.3390/medicina57080762.
5
Erythropoietin treatment and the risk of hip fractures in hemodialysis patients.促红细胞生成素治疗与血液透析患者髋部骨折风险。
J Bone Miner Res. 2021 Jul;36(7):1211-1219. doi: 10.1002/jbmr.4297. Epub 2021 May 5.
6
Effect of renal dialysis on mortality and complications following hip fracture surgery in elderly patients: A population based retrospective cohort study.肾透析对老年患者髋部骨折手术后死亡率和并发症的影响:一项基于人群的回顾性队列研究。
Medicine (Baltimore). 2020 Aug 14;99(33):e21676. doi: 10.1097/MD.0000000000021676.
7
The Influence of Renal Dialysis on All-Cause Mortality in Older Patients with Hip Fracture: a Korean Nationwide Cohort Study.老年髋部骨折患者接受肾脏透析对全因死亡率的影响:一项韩国全国队列研究。
J Korean Med Sci. 2020 Jun 22;35(24):e190. doi: 10.3346/jkms.2020.35.e190.
8
Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities.即使在控制了人口统计学因素和合并症之后,透析依赖仍与老年髋部骨折手术后围手术期不良事件的几率显著增加相关。
J Am Acad Orthop Surg Glob Res Rev. 2019 Aug 6;3(8):e086. doi: 10.5435/JAAOSGlobal-D-19-00086. eCollection 2019 Aug.
9
Hip hemiarthroplasty for femoral neck fractures in end-stage renal disease patients on dialysis compared to patients with late-stage chronic kidney disease.血液透析终末期肾病患者与晚期慢性肾脏病患者股骨颈骨折行半髋关节置换术的比较。
Singapore Med J. 2019 Aug;60(8):403-408. doi: 10.11622/smedj.2019090.
10
Chronic Kidney Disease Worsens Health Outcomes in Diabetic Patients After Hip Fracture Surgery: An Asian Nationwide Population-Based Cohort Study.慢性肾脏病使髋部骨折手术后的糖尿病患者的健康结局恶化:一项亚洲全国范围基于人群的队列研究。
J Bone Miner Res. 2019 May;34(5):849-858. doi: 10.1002/jbmr.3663. Epub 2019 Feb 11.