Public Health Post-Graduation Program, School of Medicine, Federal University of Ceará, Fortaleza, Brazil.
São José Hospital of Infectious Diseases, Fortaleza, Brasil.
AIDS Care. 2022 Dec;34(12):1580-1585. doi: 10.1080/09540121.2022.2100866. Epub 2022 Jul 21.
The frequent association between mental disorders and HIV infection may be related to several risk factors. The present study aims to determine the prevalence of depression and its associated factors in people living with HIV/AIDS (PLWHA) who attended four outpatient clinics in Fortaleza, Brazil, between September 2014 and April 2015. In addition to the Mini International Neuropsychiatric Interview questionnaire, which was used to identify the prevalence of depressive disorder, the researchers applied a sociodemographic questionnaire, and the Hamilton Depression Scale to classify the severity of depression. In all, 257 participants were included in the analyses. The overall lifetime prevalence of depression was identified to be 29.2% (19.5% in men and 44.9% in women). The prevalence of a current depressive episode was 18.7%. Mild, moderate, and severe depression was identified in 2.1%, 12.5%, and 85.4%, respectively. The factors related to depression were: gender, marital status, income, educational level, current employment status, and family history of depression. This study highlights the importance of lifetime depression as a disorder of high prevalence in PLWHA, and associated with risk factors that are difficult or impossible to be modified. Early diagnosis and treatment of depression may improve quality of life in PLWHA.
精神障碍与 HIV 感染之间的频繁关联可能与多个危险因素有关。本研究旨在确定 2014 年 9 月至 2015 年 4 月期间在巴西福塔雷萨的四个门诊诊所就诊的 HIV/AIDS(艾滋病毒/艾滋病)感染者中抑郁的患病率及其相关因素。除了用于识别抑郁障碍患病率的 Mini 国际神经精神访谈问卷外,研究人员还应用了一个社会人口学问卷和汉密尔顿抑郁量表来对抑郁的严重程度进行分类。共有 257 名参与者被纳入分析。发现抑郁的终身总患病率为 29.2%(男性为 19.5%,女性为 44.9%)。目前患有抑郁发作的患病率为 18.7%。轻度、中度和重度抑郁的比例分别为 2.1%、12.5%和 85.4%。与抑郁相关的因素包括:性别、婚姻状况、收入、教育程度、当前就业状况和抑郁家族史。本研究强调了终身抑郁作为一种高患病率障碍在艾滋病毒/艾滋病感染者中的重要性,以及与难以或不可能改变的危险因素相关。早期诊断和治疗抑郁可能会改善艾滋病毒/艾滋病感染者的生活质量。