Poudel Diptee, Acharya Kshitiz, Poudel Navin, Adhikari Ashmita, Khaniya Bishal, Maskey Suvana
Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Kathmandu, Nepal.
Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Kathmandu, Nepal.
Int J Surg Case Rep. 2022 Aug;97:107415. doi: 10.1016/j.ijscr.2022.107415. Epub 2022 Jul 16.
Though ovarian malignancies are common, mucinous ovarian carcinomas of high grade are rare. They usually occur in a young female under 40 years of age. Here, we present a case of mucinous ovarian carcinoma (stage III), with omental involvement and incidental hydronephrosis in a 67-year-old female patient.
A 67-year-old female patient presented to us with a history of lower abdominal pain for 2 months and per-vaginal discharge for the last 6 days. On deep palpation of the abdomen, a nodular mass occupying the suprapubic region was found. Bimanual palpation revealed a mass on the right and left adnexa. After visualization of septate cystic mass bilaterally on CECT, she was planned for staging laparotomy with bilateral salpingo-oophorectomy (BSO) with infra-colic omentectomy with peritoneal cytology. Incidentally, a horseshoe-shaped kidney with right mild hydronephrosis was found. After surgery and histopathologic examination, mucinous ovarian carcinoma (stage III), with omental involvement was confirmed.
Mucinous ovarian carcinomas are rare malignancies, with different natural history, molecular profile, and prognosis as compared to other epithelial tumors of the ovary. These carcinomas can be either primary or secondary (those metastasized to the ovary from elsewhere), and this differentiation is essential. The therapeutic approach to the patients depends upon the stage at which these carcinomas are diagnosed.
Mucinous ovarian carcinomas are rare and have unique features among the epithelial ovarian carcinomas. Appreciation of these features will surely make a positive impact in improving the management and thus the prognosis of these carcinomas.
尽管卵巢恶性肿瘤很常见，但高级别黏液性卵巢癌却很罕见。它们通常发生在40岁以下的年轻女性身上。在此，我们报告一例67岁女性患者的黏液性卵巢癌（III期），伴有大网膜受累及偶然发现的肾积水。
一名67岁女性患者因下腹部疼痛2个月和阴道分泌物增多6天前来就诊。腹部深部触诊发现耻骨上区域有一个结节状肿块。双合诊检查发现双侧附件有肿块。在CT增强扫描（CECT）显示双侧有分隔的囊性肿块后，计划为她进行分期剖腹手术，包括双侧输卵管卵巢切除术（BSO）、结肠下大网膜切除术及腹膜细胞学检查。偶然发现患者为马蹄肾，右侧轻度肾积水。手术及组织病理学检查后，确诊为黏液性卵巢癌（III期），伴有大网膜受累。
黏液性卵巢癌是罕见的恶性肿瘤，与卵巢其他上皮性肿瘤相比，其自然史、分子特征和预后不同。这些癌可以是原发性的，也可以是继发性的（即从其他部位转移至卵巢），这种区分至关重要。对患者的治疗方法取决于这些癌被诊断时的分期。
黏液性卵巢癌罕见，在上皮性卵巢癌中具有独特特征。认识这些特征肯定会对改善这些癌的治疗及预后产生积极影响。
