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新冠疫情的遗留问题:医院的恐惧导致了一例伴有大量腹水和广泛腹部坏死的卵巢肿瘤的诊断延迟。

The Legacy of COVID-19: Hospital Fear Led to the Delayed Diagnosis of an Ovarian Tumor with Massive Ascites and Extensive Abdominal Necrosis.

作者信息

Szederjesi Janos, Molnar Calin, Molnar-Varlam Claudiu, Dorobanțu Dorin, Pui Mihai Claudiu, Keresztes Matild

机构信息

Department of Anesthesiology and Intensive Care, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu-Mureș, 540139 Târgu Mureș, Romania.

Department of General Surgery 1, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu-Mureș, 540139 Târgu Mureș, Romania.

出版信息

Life (Basel). 2025 Apr 11;15(4):638. doi: 10.3390/life15040638.

Abstract

The COVID-19 pandemic has significantly impacted healthcare-seeking behaviors, leading to delayed cancer diagnoses due to hospital-related anxiety. This case highlights the severe consequences of delayed medical consultation in a patient with advanced ovarian cancer. A 47-year-old female presented with severe abdominal distension, massive ascites, and extensive abdominal wall necrosis after avoiding medical care for months due to severe hospital-related anxiety, exacerbated by the loss of her husband during the COVID-19 pandemic. On admission, a CT scan could not be performed due to the patient's inability to lie supine and extreme abdominal distension. To relieve pressure and improve respiratory function, an abdominal drain was inserted, releasing 72 L of ascitic fluid over five days. Following drainage, imaging confirmed a large ovarian tumor with peritoneal involvement, and a multidisciplinary team (surgeons, gynecologists, plastic surgeons, anesthetists, and intensive care specialists) determined the need for surgical intervention. Histopathology confirmed mucinous adenocarcinoma with pseudomyxoma peritonei (FIGO IIIB). This case underscores the critical impact of delayed oncological diagnosis and the need for enhanced patient education, mental health support, and structured screening programs to prevent similar late-stage presentations.

摘要

新冠疫情对就医行为产生了重大影响,因医院相关焦虑导致癌症诊断延迟。本病例凸显了晚期卵巢癌患者延迟就医咨询的严重后果。一名47岁女性因严重的医院相关焦虑,在新冠疫情期间丈夫去世后病情加重,数月来一直回避就医,就诊时出现严重腹胀、大量腹水和广泛的腹壁坏死。入院时,由于患者无法仰卧且腹胀严重,无法进行CT扫描。为减轻压力并改善呼吸功能,插入了腹腔引流管,五天内引流出72升腹水。引流后,影像学检查证实有一个伴有腹膜受累的大卵巢肿瘤,多学科团队(外科医生、妇科医生、整形外科医生、麻醉师和重症监护专家)决定需要进行手术干预。组织病理学证实为黏液性腺癌伴腹膜假黏液瘤(国际妇产科联盟IIIB期)。本病例强调了肿瘤诊断延迟的关键影响,以及加强患者教育、心理健康支持和结构化筛查项目以预防类似晚期病例的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ece/12028636/4edb1522d77b/life-15-00638-g001.jpg

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