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与 PROVE-AAA 研究中腹主动脉瘤修复选择偏好相关的因素。

Factors associated with preference of choice of aortic aneurysm repair in the PReference for Open Versus Endovascular repair of AAA (PROVE-AAA) study.

机构信息

Department of Surgery and VA Outcomes Group, White River Junction VA Medical Center, White River Junction, VT; Geisel School of Medicine at Dartmouth, Hanover, NH.

Department of Surgery and VA Outcomes Group, White River Junction VA Medical Center, White River Junction, VT; Geisel School of Medicine at Dartmouth, Hanover, NH.

出版信息

J Vasc Surg. 2022 Dec;76(6):1556-1564. doi: 10.1016/j.jvs.2022.06.018. Epub 2022 Jul 19.

DOI:10.1016/j.jvs.2022.06.018
PMID:35863555
Abstract

OBJECTIVE

Patients can choose between open repair and endovascular repair (EVAR) of abdominal aortic aneurysm (AAA). However, the factors associated with patient preference for one repair type over another are not well-characterized. Here we assess the factors associated with preference of choice for open or endovascular AAA repair among veterans exposed to a decision aid to help with choosing surgical treatment.

METHODS

Across 12 Veterans Affairs hospitals, veterans received a decision aid covering domains including patient information sources and understanding preference. Veterans were then given a series of surveys at different timepoints examining their preferences for open versus endovascular AAA repair. Questions from the preference survey were used in analyses of patient preference. Results were analyzed using χ tests. A logistic regression analysis was performed to assess factors associated with preference for open repair or preference for EVAR.

RESULTS

A total of 126 veterans received a decision aid informing them of their treatment choices, after which 121 completed all preference survey questions; five veterans completed only part of the instruments. Overall, veterans who preferred open repair were typically younger (70 years vs 73 years; P = .02), with similar rates of common comorbidities (coronary disease 16% vs 28%; P = .21), and similar aneurysms compared with those who preferred EVAR (6.0 cm vs 5.7 cm; P = .50). Veterans in both preference categories (28% of veterans preferring EVAR, 48% of veterans preferring open repair) reported taking their doctor's advice as the top box response for the single most important factor influencing their decision. When comparing the tradeoff between less invasive surgery and higher risk of long-term complications, more than one-half of veterans preferring EVAR reported invasiveness as more important compared with approximately 1 in 10 of those preferring open repair (53% vs 12%; P < .001). Shorter recovery was an important factor for the EVAR group (74%) and not important in the open repair group (76%) (P = .5). In multivariable analyses, valuing a short hospital stay (odds ratio, 12.4; 95% confidence interval, 1.13-135.70) and valuing a shorter recovery (odds ratio, 15.72; 95% confidence interval, 1.03-240.20) were associated with a greater odds of preference for EVAR, whereas finding these characteristics not important was associated with a greater odds of preference for open repair.

CONCLUSIONS

When faced with the decision of open repair versus EVAR, veterans who valued a shorter hospital stay and a shorter recovery were more likely to prefer EVAR, whereas those more concerned about long-term complications preferred an open repair. Veterans typically value the advice of their surgeon over their own beliefs and preferences. These findings need to be considered by surgeons as they guide their patients to a shared decision.

摘要

目的

患者可以在开放修复和血管内修复(EVAR)治疗腹主动脉瘤(AAA)之间进行选择。然而,与患者对一种修复类型的偏好而不是另一种修复类型的偏好相关的因素尚不清楚。在这里,我们评估了在接受帮助选择手术治疗的决策辅助工具后,退伍军人对开放或血管内 AAA 修复选择的偏好相关因素。

方法

在 12 家退伍军人事务医院中,退伍军人接受了涵盖患者信息来源和偏好理解等领域的决策辅助工具。然后,退伍军人在不同时间点接受了一系列调查,调查他们对开放与血管内 AAA 修复的偏好。偏好调查中的问题用于分析患者的偏好。使用 χ 检验分析结果。进行逻辑回归分析以评估与开放修复或 EVAR 偏好相关的因素。

结果

共有 126 名退伍军人收到了告知他们治疗选择的决策辅助工具,之后 121 名退伍军人完成了所有偏好调查问题;5 名退伍军人仅完成了部分仪器。总体而言,选择开放修复的退伍军人通常更年轻(70 岁 vs 73 岁;P =.02),常见合并症的发生率相似(冠心病 16% vs 28%;P =.21),并且与选择 EVAR 的退伍军人相似(6.0 cm vs 5.7 cm;P =.50)。在这两个偏好类别中的退伍军人(28%的退伍军人更喜欢 EVAR,48%的退伍军人更喜欢开放修复)报告将医生的建议作为影响他们决策的最重要因素的首选。当比较微创手术和长期并发症风险较高之间的权衡时,超过一半选择 EVAR 的退伍军人报告侵入性更重要,而选择开放修复的退伍军人中只有大约十分之一的人认为侵入性更重要(53% vs 12%;P<.001)。较短的恢复期对 EVAR 组很重要(74%),对开放修复组不重要(76%)(P =.5)。在多变量分析中,重视短期住院(优势比,12.4;95%置信区间,1.13-135.70)和重视较短的恢复期(优势比,15.72;95%置信区间,1.03-240.20)与 EVAR 的偏好几率增加相关,而认为这些特征不重要与对开放修复的偏好几率增加相关。

结论

当面临开放修复与 EVAR 的选择时,重视短期住院和较短恢复期的退伍军人更有可能选择 EVAR,而那些更担心长期并发症的退伍军人则更倾向于选择开放修复。退伍军人通常更看重外科医生的建议,而不是自己的信念和偏好。外科医生在指导患者做出共同决策时需要考虑这些发现。

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