From the Departments of Diagnostic and Interventional Radiology (Q.-H.T., T.W., C.-G.W.).
Oncology (K.-H., D.-L.M.), Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
AJNR Am J Neuroradiol. 2022 Aug;43(8):1222-1227. doi: 10.3174/ajnr.A7587. Epub 2022 Jul 21.
Percutaneous sacroplasty is a variation of percutaneous vertebroplasty that has gained attention as a therapeutic option for patients with painful sacral insufficiency fractures due to osteoporosis or metastases. Additionally, percutaneous sacroplasty can also be used to treat painful sacral metastases without a pathologic fracture. The purpose of this retrospective study was to compare the efficacy and safety of fluoroscopy-guided percutaneous sacroplasty alone versus percutaneous sacroplasty plus radiofrequency ablation for the treatment of painful sacral metastases.
For this retrospective study, 126 patients (with a total of 162 painful sacral metastases) were enrolled from October 2012 to February 2021 and assigned to receive either percutaneous sacroplasty plus radiofrequency ablation ( = 51, group A) or percutaneous sacroplasty alone ( = 75, group B). Four different approaches were used for percutaneous sacroplasty: transiliac, interpedicular, anterior-oblique, and posterior. The Visual Analog Scale, Oswestry Disability Index, and Karnofsky Performance Scale were used to evaluate outcomes.
The Visual Analog Scale, Oswestry Disability Index, and Karnofsky Performance Scale scores showed significant improvement in both groups after treatment (< .05). The overall pain relief rate was significantly better in group A than in group B (90% versus 76%, = .032). There were no significant differences in the incidence of polymethylmethacrylate leakage between the 2 groups or among the 4 different approaches (> .05).
Both percutaneous sacroplasty alone and the combination of percutaneous sacroplasty and radiofrequency ablation are safe and effective for treatment of painful sacral metastases. The combination of percutaneous sacroplasty and radiofrequency ablation appears to be more effective than percutaneous sacroplasty alone.
经皮骶骨成形术是经皮椎体成形术的一种变体,已作为骨质疏松或转移引起的疼痛性骶骨不稳定性骨折的治疗选择引起关注。此外,经皮骶骨成形术也可用于治疗无病理性骨折的疼痛性骶骨转移。本回顾性研究的目的是比较单纯透视引导经皮骶骨成形术与经皮骶骨成形术联合射频消融术治疗疼痛性骶骨转移的疗效和安全性。
本回顾性研究纳入了 2012 年 10 月至 2021 年 2 月期间的 126 例(共 162 个疼痛性骶骨转移)患者,并分为接受经皮骶骨成形术联合射频消融术(n=51,A 组)或单纯经皮骶骨成形术(n=75,B 组)的患者。经皮骶骨成形术采用 4 种不同的入路:髂骨入路、椎弓根入路、前斜入路和后入路。采用视觉模拟评分法(VAS)、Oswestry 功能障碍指数(ODI)和卡氏功能状态评分(KPS)评估疗效。
两组治疗后 VAS、ODI 和 KPS 评分均明显改善(均<.05)。A 组的总体疼痛缓解率明显优于 B 组(90%比 76%,<.032)。两组之间以及 4 种不同入路之间的聚甲基丙烯酸甲酯渗漏发生率无显著差异(>.05)。
单纯经皮骶骨成形术和经皮骶骨成形术联合射频消融术均安全有效,可用于治疗疼痛性骶骨转移。经皮骶骨成形术联合射频消融术似乎比单纯经皮骶骨成形术更有效。