Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Semin Perinatol. 2022 Nov;46(7):151637. doi: 10.1016/j.semperi.2022.151637. Epub 2022 Jun 10.
For more than 30 years, the Neonatal Research Network (NRN) has conducted studies addressing the epidemiology of neonatal infections, including incidence, microbiology, maternal and neonatal risk factors, associated clinical findings, and outcomes. These studies have provided clinicians and policymakers critical data needed to inform national guidance for infection risk assessment and support daily practice. Further, NRN studies have prompted research into optimal approaches to infection diagnosis, treatment, and antimicrobial stewardship. In this article, we summarize the key findings of NRN infection-related studies, with an emphasis on those published in 2000 or later.
三十多年来，新生儿研究网络（NRN）开展了多项研究，旨在探讨新生儿感染的流行病学，包括感染的发生率、微生物学、母婴危险因素、相关临床发现和结局。这些研究为临床医生和决策者提供了重要数据，为感染风险评估的国家指南提供了信息，并支持了日常实践。此外，NRN 的研究还促使人们研究感染诊断、治疗和抗菌药物管理的最佳方法。本文总结了 NRN 与感染相关的研究的主要发现，重点介绍了 2000 年或之后发表的研究。
