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创伤性上肢截肢后早期对臂丛神经进行冷冻镇痛可预防幻肢痛的发生:一例报告。

Early application of cryoanalgesia to the brachial plexus prevents development of phantom limb pain after traumatic forequarter amputation: A case report.

作者信息

O'Connor Lizabeth A, Houseman Bryan, Taffe Daniel, Quinn Curtis C

机构信息

Elliot Health System, Division of Thoracic Surgery, 1 Elliot Way, Manchester, NH 03103, United States.

Elliot Health System, Division of Orthopedic Trauma, 1 Elliot Way, Manchester, NH 03103, United States.

出版信息

Trauma Case Rep. 2022 Jul 13;41:100678. doi: 10.1016/j.tcr.2022.100678. eCollection 2022 Oct.

DOI:10.1016/j.tcr.2022.100678
PMID:35864840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9294552/
Abstract

BACKGROUND

Amputation of an extremity frequently results in significant phantom limb pain. The etiology of which is not well understood. Central and peripheral factors appear to play a role. Pain relief interventions often are attempted several weeks to months later. Peripheral nerve injury can rapidly result in cortical somatosensory changes potentially making early intervention important in preventing any permanent changes in nerve pathways.

CASE REPORT

We present a case of traumatic forequarter (interscapulothoracic) amputation treated with cryoanalgesia of the brachial plexus for pain control <72 h after injury. The patient denied painful phantom limb pain and postoperative pain at the surgical site immediately following surgery and over a six month follow up period.

CONCLUSION

Cryoanalgesia facilitates extended duration of pain control of the affected peripheral nerve which may be of particular benefit in patients sustaining either surgical or traumatic amputations, particularly when applied early to prevent the transmission of noxious signals to the central nervous system.

摘要

背景

肢体截肢常常导致严重的幻肢痛。其病因尚未完全明确。中枢和外周因素似乎都发挥着作用。疼痛缓解干预措施通常在数周或数月后才尝试实施。外周神经损伤可迅速导致皮质体感变化,这可能使早期干预对于预防神经通路的任何永久性改变至关重要。

病例报告

我们报告一例创伤性前半侧肢体(肩胛胸壁间)截肢病例,在受伤后<72小时采用臂丛神经冷冻镇痛法控制疼痛。术后即刻及六个月的随访期间,患者均否认有疼痛性幻肢痛及手术部位的术后疼痛。

结论

冷冻镇痛有助于延长对受影响外周神经的疼痛控制时间,这对于接受手术或创伤性截肢的患者可能特别有益,尤其是在早期应用以防止有害信号向中枢神经系统传递时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/4a43a9cc3778/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/681e3084c9c3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/8ac973e97724/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/171466e38337/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/4a43a9cc3778/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/681e3084c9c3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/8ac973e97724/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/171466e38337/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/9294552/4a43a9cc3778/gr4.jpg

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Surgical stabilization of rib fractures combined with intercostal nerve cryoablation proves to be more cost effective by reducing hospital length of stay and narcotics.手术固定肋骨骨折并结合肋间神经冷冻消融术可降低住院时间和减少麻醉性镇痛药的使用,从而更具成本效益。
Injury. 2021 May;52(5):1128-1132. doi: 10.1016/j.injury.2021.02.009. Epub 2021 Feb 6.
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Postoperative pain control modalities for pectus excavatum repair: A prospective observational study of cryoablation compared to results of a randomized trial of epidural vs patient-controlled analgesia.
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J Pediatr Surg. 2020 Aug;55(8):1444-1447. doi: 10.1016/j.jpedsurg.2019.09.021. Epub 2019 Oct 26.
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Treatment of phantom limb pain by cryoneurolysis of the amputated nerve.通过对截肢神经进行冷冻神经lysis治疗幻肢痛。 (注:这里“lysis”常见释义为“分解”“溶解”等,结合语境可能是冷冻神经消融之类的专业术语,由于不清楚确切专业含义,保留英文更合适)
Pain Pract. 2014 Jan;14(1):52-6. doi: 10.1111/papr.12020. Epub 2012 Dec 19.
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Phantom limb pain: mechanisms and treatment approaches.幻肢痛:机制与治疗方法
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