Küster M, Wahn U
Klin Padiatr. 1987 Mar-Apr;199(2):108-10. doi: 10.1055/s-2008-1026773.
Long time treatment of asthma in children with theophylline requires therapeutic drug monitoring by determination of serum concentrations. Beside established assays a carrier-bound reagent test has recently been developed, which has been demonstrated to be accurate, precise and cheaper than other assays. It has the advantage to give rapid results within minutes, which makes it suitable for intensive care units as well as for outpatient care.
长期使用茶碱治疗儿童哮喘需要通过测定血清浓度进行治疗药物监测。除了已有的检测方法外,最近还开发了一种载体结合试剂检测法,已证明该方法准确、精密且比其他检测方法更便宜。其优点是能在几分钟内给出快速结果,这使其适用于重症监护病房以及门诊护理。