Department of Orthopedic Surgery, Okayama Red Cross Hospital, Okayama, Japan.
Department of Orthopedic Surgery, Okayama University Hospital, Okayama, Japan.
Medicine (Baltimore). 2022 Jul 22;101(29):e29568. doi: 10.1097/MD.0000000000029568.
Early sarcopenia detection using screening tools, such as SARC-F and SARC-CalF, has been proven reliable. However, the relationship between chronic musculoskeletal pain with sarcopenia is unknown. This study assessed sarcopenia morbidity as well as the reliability of sarcopenia screening with SARC-F and SARC-CalF in patients with chronic musculoskeletal pain.
Overall, 172 patients with chronic musculoskeletal pain were included in this cross-sectional study. All participants completed the SARC-F, SARC-CalF, numeric rating scale (NRS), and pain disability assessment scale (PDAS) assessments. Sarcopenia was diagnosed using the Asian Working Group for Sarcopenia criteria 2019. Correlations between SARC-F and SARC-CalF scores and each measured variable were evaluated using univariate and multiple linear regression analyses. A receiver operating characteristic curve analysis was conducted, and reliabilities of SARC-F and SARC-CalF scores for diagnosing sarcopenia were compared.
Thirty-nine patients were diagnosed with sarcopenia. Among these, 10 patients were <65 years old, and 29 were >65 years old. Both SARC-F and SARC-CalF scores significantly correlated with grip power, gait speed, skeletal mass index, numeric rating scale score, and PDAS score. In multiple linear regression analysis, SALC-F and SALC-CalF scores significantly correlated with PDAS score, skeletal mass index, and gait speed. The area under the curve were 0.70 for SARC-F and 0.88 for SARC-CalF; SARC-CalF had a significantly higher area under the curve than SARC-F.
Sarcopenia was diagnosed in patients aged <65 years with chronic musculoskeletal pain. SALC-F and SARC-CalF scores showed a significant correlation with disability due to pain and were reliable sarcopenia screening tools for chronic musculoskeletal pain. SARC-CalF was more reliable than SARC-F.
使用 SARC-F 和 SARC-CalF 等筛查工具早期检测肌少症已被证明是可靠的。然而，慢性肌肉骨骼疼痛与肌少症之间的关系尚不清楚。本研究评估了慢性肌肉骨骼疼痛患者的肌少症发病率，以及 SARC-F 和 SARC-CalF 筛查肌少症的可靠性。
本横断面研究共纳入 172 例慢性肌肉骨骼疼痛患者。所有参与者均完成了 SARC-F、SARC-CalF、数字评分量表（NRS）和疼痛残疾评估量表（PDAS）评估。使用 2019 年亚洲肌少症工作组标准诊断肌少症。使用单变量和多元线性回归分析评估 SARC-F 和 SARC-CalF 评分与各测量变量之间的相关性。进行受试者工作特征曲线分析，并比较 SARC-F 和 SARC-CalF 评分诊断肌少症的可靠性。
39 例患者被诊断为肌少症。其中，10 例患者年龄<65 岁，29 例患者年龄>65 岁。SARC-F 和 SARC-CalF 评分均与握力、步态速度、骨骼质量指数、NRS 评分和 PDAS 评分显著相关。多元线性回归分析显示，SARC-F 和 SARC-CalF 评分与 PDAS 评分、骨骼质量指数和步态速度显著相关。SARC-F 的曲线下面积为 0.70，SARC-CalF 的曲线下面积为 0.88；SARC-CalF 的曲线下面积显著高于 SARC-F。
本研究诊断了年龄<65 岁的慢性肌肉骨骼疼痛患者的肌少症。SARC-F 和 SARC-CalF 评分与疼痛导致的残疾显著相关，是慢性肌肉骨骼疼痛可靠的肌少症筛查工具。SARC-CalF 比 SARC-F 更可靠。
