Department of Plastic and Reconstructive Surgery, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University
Eur J Dermatol. 2022 Apr 1;32(2):244-248. doi: 10.1684/ejd.2022.4223.
Laser treatment for congenital melanocytic nevi (CMN) is controversial. Correlations between anatomical distribution of facial CMN and efficacy of laser treatment have not been characterized.
MATERIALS & METHODS: A total of 90 facial CMN treated with ablative laser (Er:YAG or CO2 laser) were retrospectively reviewed. Clinical assessments were completed by at least two plastic surgeons using the Investigator’s Global Assessment (IGA) score.
The mean IGA score was 4.37. The IGA scores recorded at the periorbital, temple/forehead, nose, cheek and lip/chin areas were 3.68, 5.88, 4.63, 4.52 and 4.92, respectively (p = 0.03). Moreover, facial CMN with uniform pigment distribution showed higher IGA scores than those with a non-uniform pigment distribution. Thickening, hairiness and age at first treatment were not statistically correlated with laser efficacy.
Correlations between anatomical distribution and the efficacy of laser treatment are described for the first time. The subdivided anatomical distribution of facial CMN can yield meaningful information on predicting the efficacy of laser treatment.
激光治疗先天性黑色素痣（CMN）存在争议。面部 CMN 的解剖分布与激光治疗效果之间的相关性尚未明确。
回顾性分析了 90 例接受消融性激光（Er:YAG 或 CO2 激光）治疗的面部 CMN。由至少两名整形外科医生使用研究者全球评估（IGA）评分完成临床评估。
平均 IGA 评分为 4.37。眶周、颞部/额部、鼻部、颊部和唇/颏部的 IGA 评分分别为 3.68、5.88、4.63、4.52 和 4.92（p = 0.03）。此外，色素分布均匀的面部 CMN 的 IGA 评分高于色素分布不均匀的 CMN。增厚、多毛和首次治疗时的年龄与激光疗效无统计学相关性。
首次描述了面部 CMN 解剖分布与激光治疗效果之间的相关性。面部 CMN 的细分解剖分布可提供有意义的信息，有助于预测激光治疗的效果。
