冷冻电子断层成像术：通往细胞内部空间的漫长旅程。
Cryo-electron tomography: A long journey to the inner space of cells.
机构信息
Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.
出版信息
Cell. 2022 Jul 21;185(15):2649-2652. doi: 10.1016/j.cell.2022.06.034.
PMID:35868271
Abstract
Cryogenic electron tomography (cryo-ET) is the application of tomographic principles of data acquisition and reconstruction to frozen-hydrated biological specimens. It combines a close-to-life preservation of cellular structures with the power of high-resolution three-dimensional imaging, which allows us to study the molecular architecture of cells, or their molecular sociology, in unprecedented detail.
摘要
低温电子断层扫描（cryo-ET）是将断层扫描的数据采集和重建原理应用于冷冻水合生物样本。它将细胞结构的近乎生命的保存与高分辨率三维成像的强大功能相结合，使我们能够以前所未有的细节研究细胞的分子结构，或它们的分子社会学。
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