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[慢性肝病的中心血流动力学变化(放射心脏病学研究)]

[Changes in central hemodynamics in chronic liver diseases (radiocardiologic study)].

作者信息

Loginov A S, Khodarev N N, Astaf'eva O V, Sakharova G N

出版信息

Med Radiol (Mosk). 1987 Apr;32(4):26-30.

PMID:3586907
Abstract

Some indices of central hemodynamics: cardiac and systolic indices, specific peripheral resistance and circulating plasma and blood volumes were studied in 136 patients with chronic liver diseases using radionuclide cardiography. I. Three hemodynamic types of blood circulation (hyper-, eu- and hypokinetic) were defined in patients with chronic liver diseases as well as in healthy persons. II. In liver cirrhosis and ascites the number of patients with the hyperkinetic type of circulation increased significantly, mainly at the expense of patients with hypervolemia. III. A significant decrease in circulating plasma and blood volumes was noted in patients with liver cirrhosis complicated by ascites, with the hypokinetic type of circulation. It should be borne in mind in administration of diuretics to such patients. The above results suggested that different types of circulation in patients with chronic liver diseases were formed under the influence of the disease against a background of existing constitutionally and genetically determined hemodynamic heterogeneity.

摘要

运用放射性核素心动图对136例慢性肝病患者的一些中心血流动力学指标:心功能和收缩功能指标、外周比阻力以及循环血浆和血容量进行了研究。一、慢性肝病患者以及健康人群中确定了三种血液循环的血流动力学类型(高动力型、正常动力型和低动力型)。二、在肝硬化和腹水患者中,高动力型循环的患者数量显著增加,主要是以血容量过多的患者为代价。三、在伴有腹水的肝硬化患者中,低动力型循环的患者出现循环血浆和血容量显著减少。在给这类患者使用利尿剂时应予以考虑。上述结果表明,慢性肝病患者不同类型的循环是在疾病的影响下,在现有的体质和遗传决定的血流动力学异质性背景下形成的。

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