Jiangxi Maternal and Child Health Hospital.
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Cell Mol Biol (Noisy-le-grand). 2022 Feb 28;68(2):126-131. doi: 10.14715/cmb/2022.68.2.18.
Infertility is still a hot topic in the field of reproductive medicine. In this paper, the detection of vaginal secretions and the positive rate of serum reproductive immune antibody in infertile women and normal pregnant women were used to explore the correlation between infertility and the two, so as to provide an effective scientific basis for the diagnosis and treatment of infertility. In this paper, 80 infertile patients (experimental group) and normal pregnant women (control group) were selected for the experiment. Real-time PCR was used to detect vaginal secretion and enzyme-linked immunosorbent assay. The results showed that the positive rates of UU and CT were 42.5% and 40%, respectively. The positive rate of the control group was 8.8% (Uu) and 7.5% (CT). In addition, the positive rates of ANA and AsAb in the experimental group were 40% and 44%, respectively, and those in the control group were 7.5% and 8.8%, respectively, with a significant difference (P<0.01). The correlation coefficients between the two antibodies and the occurrence of infertility were 0.501 (ANA) and 0.663 (AsAb), and there was a correlation (P<0.05).
不孕仍然是生殖医学领域的热门话题。本文通过检测不孕妇女和正常孕妇的阴道分泌物及血清生殖免疫抗体的阳性率，探讨不孕与两者的相关性，为不孕的诊断和治疗提供有效的科学依据。本研究选取 80 例不孕患者（实验组）和正常孕妇（对照组）进行实验。采用实时荧光定量 PCR 法检测阴道分泌物，酶联免疫吸附法检测血清生殖免疫抗体。结果显示，UU 和 CT 的阳性率分别为 42.5%和 40%，对照组的阳性率分别为 8.8%（Uu）和 7.5%（CT）。此外，实验组 ANA 和 AsAb 的阳性率分别为 40%和 44%，对照组分别为 7.5%和 8.8%，差异有统计学意义（P<0.01）。两种抗体与不孕的发生呈正相关，相关系数分别为 0.501（ANA）和 0.663（AsAb）（P<0.05）。
