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通过即时检验诊断犬鹅膏毒肽中毒(鹅膏毒素中毒)的早期诊断

Early diagnosis of amanitin exposure (amatoxicosis) in a dog with a point-of-care diagnostic test.

作者信息

Kaae Jennifer A, Bever Candace S, Poppenga Robert H

机构信息

Pet Emergency and Specialty Center of Marin, San Rafael, California, USA.

Foodborne Toxin Detection and Prevention Research Unit, Agricultural Research Service (ARS), United States Department of Agriculture (USDA), Albany, California, USA.

出版信息

J Vet Emerg Crit Care (San Antonio). 2022 Nov;32(6):824-829. doi: 10.1111/vec.13235. Epub 2022 Jul 23.

DOI:10.1111/vec.13235
PMID:35869756
Abstract

OBJECTIVE

To describe the rapid diagnosis, treatment, and clinical course of a dog that ingested an amanitin-containing mushroom.

CASE SUMMARY

A 2-month-old female intact Australian Shepherd presented with diarrhea and vomiting, along with a possible mushroom exposure. Upon presentation, the dog's urine was collected and tested positive by a point-of-care rapid diagnostic test specific for detecting amanitins, the causative agents of amatoxicosis.

NEW OR UNIQUE INFORMATION PROVIDED

This is the first reported case of amatoxicosis that was diagnosed using a point-of-care test prior to starting treatment. An early diagnosis helps to guide early treatment decisions in this frequently fatal toxicosis.

摘要

目的

描述一只摄入含鹅膏毒素蘑菇的犬的快速诊断、治疗及临床病程。

病例摘要

一只2月龄未绝育的雌性澳大利亚牧羊犬出现腹泻和呕吐,可能接触过蘑菇。就诊时,采集了该犬的尿液,通过一种用于检测鹅膏毒素(鹅膏中毒的致病因子)的即时快速诊断检测呈阳性。

提供的新的或独特信息

这是首例在开始治疗前通过即时检测诊断出鹅膏中毒的病例。早期诊断有助于指导这种常致命的中毒的早期治疗决策。

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Case Report: α-amanitin toxicosis leading to acute death in a puppy.病例报告:一只幼犬因α-鹅膏蕈碱中毒导致急性死亡。
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Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication.一只狗在从α-鹅膏毒肽中毒恢复后出现肾上腺皮质功能减退。
Vet Sci. 2023 Aug 3;10(8):500. doi: 10.3390/vetsci10080500.