Taylor Cullen M, Marino Michael J, Bansberg Stephen F
Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, U.S.A.
Laryngoscope. 2023 Jun;133(6):1315-1320. doi: 10.1002/lary.30299. Epub 2022 Jul 23.
To objectively identify and quantitate presenting nasal symptoms in patients with a septal perforation using the validated NOSE-Perf scale.
Case series retrospective review.
The medical records from August 2018 through January 2022 of patients at a tertiary care academic center with a septal perforation, and who completed the NOSE-Perf questionnaire, were reviewed. Perforation symptoms were identified and quantified using the 12-item NOSE-Perf scale (score range 0-48). NOSE-Perf findings were correlated to patient demographics, perforation etiology, and perforation length. NOSE-Perf scores of patients who pursued treatment were compared with those who did not.
NOSE-Perf data were collected from 202 patients. Nasal crusting was noted in 94.1% of patients and was the most severe symptom reported (mean 2.9 of 4.0). Nasal congestion, difficulty breathing, and nasal obstruction followed in prevalence and severity. The mean total NOSE-Perf score was 23.7. Linear regression analysis demonstrated a weakly negative association of NOSE-Perf score with patient age and weakly positive association with increasing perforation length. NOSE-Perf scores were significantly higher in women and in patients pursuing treatment.
This is the first study to use the validated NOSE-Perf scale to objectively characterize and establish baseline septal perforation symptomatology. The NOSE-Perf scale can play a role in the standardization of perforation evaluation and treatment outcomes assessment. Laryngoscope, 133:1315-1320, 2023.
使用经过验证的鼻中隔穿孔鼻症状评分量表（NOSE-Perf量表）客观识别和量化鼻中隔穿孔患者出现的鼻部症状。
病例系列回顾性研究。
回顾了2018年8月至2022年1月在一家三级医疗学术中心患有鼻中隔穿孔且完成了NOSE-Perf问卷的患者的病历。使用12项NOSE-Perf量表（评分范围0 - 48）识别并量化穿孔症状。将NOSE-Perf量表的结果与患者人口统计学特征、穿孔病因及穿孔长度进行关联分析。比较了接受治疗的患者与未接受治疗的患者的NOSE-Perf评分。
收集了202例患者的NOSE-Perf数据。94.1%的患者存在鼻痂，这是报告中最严重的症状（平均4.0分中的2.9分）。鼻充血、呼吸困难和鼻塞在患病率和严重程度方面紧随其后。NOSE-Perf量表的平均总评分为23.7分。线性回归分析表明，NOSE-Perf量表评分与患者年龄呈弱负相关，与穿孔长度增加呈弱正相关。女性患者和接受治疗的患者的NOSE-Perf评分显著更高。
这是第一项使用经过验证的NOSE-Perf量表客观描述鼻中隔穿孔症状并建立基线症状学的研究。NOSE-Perf量表可在穿孔评估标准化和治疗效果评估中发挥作用。《喉镜》，2023年，133卷：1315 - 1320页。
