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鼻中隔穿孔的NOSE-Perf量表验证:一项与鼻阻塞对照的跨文化研究。

Validation of the NOSE-Perf Scale for Nasal Septal Perforation: A Cross-Cultural Study With a Nasal Obstruction Comparator.

作者信息

Kwon Kyung Won, Jin Mi Hyeon, Ko Nak Gyeong

机构信息

Department of Otolaryngology Samsung Changwon Hospital, University of Sungkyunkwan, College of Medicine Changwon Korea.

Department of Research & Support Samsung Changwon Hospital, Sungkyunkwan University School of Medicine Changwon Korea.

出版信息

Laryngoscope Investig Otolaryngol. 2025 Aug 2;10(4):e70218. doi: 10.1002/lio2.70218. eCollection 2025 Aug.

DOI:10.1002/lio2.70218
PMID:40756701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12317365/
Abstract

OBJECTIVES

Nasal septal perforation (NSP) presents complex diagnostic and therapeutic challenges, particularly due to the absence of a validated, symptom-specific patient-reported outcome measure. The nasal obstruction symptom evaluation-perforation (NOSE-Perf) scale was recently developed to address this gap. This study aimed to cross-culturally validate the Korean version of the NOSE-Perf scale and evaluate its clinical utility in distinguishing NSP-related symptoms.

METHODS

The 12-item NOSE-Perf scale, which includes five NOSE items and seven additional, non-obstruction-related questions, was translated into Korean. Thirty-six patients with NSP, 40 with nasal obstruction only, and 40 control patients with no rhinologic symptoms completed the questionnaire. The scale's internal consistency, test-retest reliability, and validity were evaluated.

RESULTS

The most commonly reported symptoms on the NOSE-Perf scale among patients with NSP were nasal congestion and obstruction (32/36 for each), followed by nasal crusting and difficulty breathing through the nose. The scale demonstrated good internal consistency (Cronbach's  = 0.789) and high test-retest reliability ( < 0.001). The mean NOSE-Perf scale scores differed significantly across the three groups ( < 0.001), with the highest scores in patients with NSP, followed by those in the nasal obstruction and control groups (16.97 vs. 13.03 vs. 1.30, respectively). Conversely, the NOSE scale score was the highest in the nasal obstruction group, followed by those in the NSP and control groups (12.20 vs. 8.72 vs. 0.50, respectively).

CONCLUSION

The Korean version of the NOSE-Perf scale is a valid and reliable assessment tool for NSP in Korean patients, facilitating more accurate diagnosis and treatment evaluation compared with the NOSE scale.

LEVEL OF EVIDENCE

Not applicable.

摘要

目的

鼻中隔穿孔(NSP)带来了复杂的诊断和治疗挑战,尤其是因为缺乏经过验证的、针对症状的患者报告结局测量方法。鼻阻塞症状评估 - 穿孔(NOSE - Perf)量表最近被开发出来以填补这一空白。本研究旨在对NOSE - Perf量表的韩语版本进行跨文化验证,并评估其在区分NSP相关症状方面的临床效用。

方法

将包含5个NOSE项目和7个额外的、与阻塞无关问题的12项NOSE - Perf量表翻译成韩语。36例NSP患者、40例仅患有鼻阻塞的患者和40例无鼻科症状的对照患者完成了问卷。对该量表的内部一致性、重测信度和效度进行了评估。

结果

NSP患者中,NOSE - Perf量表上最常报告的症状是鼻塞和鼻阻塞(各32/36),其次是鼻痂和经鼻呼吸困难。该量表显示出良好的内部一致性(Cronbach's α = 0.789)和高重测信度(P < 0.001)。三组之间的平均NOSE - Perf量表得分差异显著(P < 0.001),NSP患者得分最高,其次是鼻阻塞组和对照组(分别为16.97、13.03和1.30)。相反,NOSE量表得分在鼻阻塞组最高,其次是NSP组和对照组(分别为12.20、8.72和0.50)。

结论

NOSE - Perf量表的韩语版本是评估韩国患者NSP的有效且可靠的工具,与NOSE量表相比,有助于更准确的诊断和治疗评估。

证据水平

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/986bbed863ab/LIO2-10-e70218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/7b2c7abae8f2/LIO2-10-e70218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/963a7d7387e0/LIO2-10-e70218-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/986bbed863ab/LIO2-10-e70218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/7b2c7abae8f2/LIO2-10-e70218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/963a7d7387e0/LIO2-10-e70218-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e035/12317365/986bbed863ab/LIO2-10-e70218-g002.jpg

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本文引用的文献

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Translation, cultural adaptation, and validation of the NOSE-Perf scale to Brazilian Portuguese.NOSE-Perf 量表的翻译、文化调适与验证至巴西葡萄牙文。
Braz J Otorhinolaryngol. 2024 Sep-Oct;90(5):101442. doi: 10.1016/j.bjorl.2024.101442. Epub 2024 May 16.
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Validated Symptom Outcomes Following Septal Perforation Repair: Application of the NOSE-Perf Scale.
鼻中隔穿孔修复术后验证症状结果:NOSE-Perf 量表的应用。
Laryngoscope. 2024 Jul;134(7):3067-3072. doi: 10.1002/lary.31329. Epub 2024 Feb 9.
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Impact of nasal septal perforation on the airflow and air-conditioning characteristics of the nasal cavity.鼻中隔穿孔对鼻腔气流和空调特性的影响。
Sci Rep. 2024 Jan 29;14(1):2337. doi: 10.1038/s41598-024-52755-4.
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Presenting Symptomatology for Patients With Nasal Septal Perforation: Application of the NOSE-Perf Scale.鼻中隔穿孔患者的症状表现:NOSE-Perf量表的应用
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