Department of Physics, Faculty of Sciences, University of Guilan, 41335-1914 Rasht, Iran.
Radiat Prot Dosimetry. 2022 Sep 22;198(16):1244-1257. doi: 10.1093/rpd/ncac158.
Renal scintigraphy plays an important role in the diagnosis of various kidney disorders. This procedure can be performed with different radiopharmaceuticals. The patients undergoing renal scintigraphy receive a radiation dose that should be assessed. In this study, the effective dose of patients due to renal scintigraphy with 99mTc (DMSA, DTPA, EC and MAG3) was calculated for the International Commission on Radiological Protection (ICRP) 110 adult reference phantoms using the Medical Internal Radiation Dose method and the ICRP 60 and 103 tissue weighting factors. The results show that the highest effective dose per unit activity administered is due to 99mTc DMSA. On average, the effective dose per unit activity administered of 99mTc DMSA is almost twice the effective dose per unit activity administered of other radiopharmaceuticals. The effective doses per unit activity administered calculated using the ICRP 103 tissue weighting factors are always lower than that calculated using the ICRP 60 tissue weighting factors and the ICRP 128 data.
肾闪烁显像术在各种肾脏疾病的诊断中起着重要作用。该过程可以使用不同的放射性药物进行。接受肾闪烁显像术的患者会接受一定剂量的辐射，应进行评估。在这项研究中，使用 Medical Internal Radiation Dose 方法和 ICRP 60 和 103 组织权重因子，为国际辐射防护委员会 (ICRP) 的 110 个成人参考体模计算了因 99mTc（DMSA、DTPA、EC 和 MAG3）肾闪烁显像术而导致的患者有效剂量。结果表明，单位活度给予的最高有效剂量归因于 99mTc DMSA。平均而言，单位活度给予的 99mTc DMSA 的有效剂量几乎是其他放射性药物单位活度给予的有效剂量的两倍。使用 ICRP 103 组织权重因子计算的单位活度给予的有效剂量始终低于使用 ICRP 60 组织权重因子和 ICRP 128 数据计算的有效剂量。
