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采用质量改进方法进行广谱抗生素管理。

Broad spectrum antibiotic stewardship by quality improvement methods.

机构信息

Antibiotic Specialist Pharmacist, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, UK.

GP Partner, Lockside Medical Centre, Stalybridge, UK.

出版信息

Int J Risk Saf Med. 2022;33(S1):S35-S40. doi: 10.3233/JRS-227021.

DOI:10.3233/JRS-227021
PMID:35871365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9844069/
Abstract

BACKGROUND

With the majority of antibiotics being prescribed in primary care it is of utmost importance that antimicrobial stewardship principles are adhered to in order to slow down the incidence of antimicrobial resistance.

OBJECTIVE

Broad spectrum antibiotic prescribing is often seen as a proxy marker of increasing resistance within a population and so it is important that they are used sparingly, to avoid drug-resistant bacteria developing.

METHOD

In Tameside and Glossop a novel approach, using quality improvement methods, was employed to allow the behaviour change to be sustained for a longer period. Practices submitted monthly broad spectrum usage data, and if over a set target they were required to submit a "deep dive".

RESULTS

A 10.6% reduction of broad spectrum antibiotic usage was seen over the 2019-20 financial year.

CONCLUSION

Over time the number of practices submitting a deep dive reduced and clinicians saw the deep dive as method to peer review their prescribing. Putting the practice staff in control of their own prescribing, allowed for a better method to sustain the improvement.

摘要

背景

由于大多数抗生素都是在初级保健中开具的,因此遵守抗菌药物管理原则对于减缓抗菌药物耐药性的发生至关重要。

目的

广谱抗生素的使用通常被视为人群中耐药性增加的代理指标,因此,为了避免耐药细菌的产生,应谨慎使用。

方法

在塔姆斯代尔和格洛索普,采用了一种新的方法,利用质量改进方法,使行为改变能够持续更长时间。各实践每月提交广谱药物使用数据,如果超过设定目标,则需要提交“深度调查”。

结果

在 2019-20 财政年度,广谱抗生素的使用减少了 10.6%。

结论

随着时间的推移,提交深度调查的实践数量减少,临床医生将深度调查视为同行评审其处方的一种方法。让实践工作人员控制自己的处方,为持续改进提供了更好的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/9844069/253d3ea89d5c/jrs-33-jrs227021-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/9844069/2824aff81fbc/jrs-33-jrs227021-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/9844069/253d3ea89d5c/jrs-33-jrs227021-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/9844069/2824aff81fbc/jrs-33-jrs227021-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/9844069/253d3ea89d5c/jrs-33-jrs227021-g002.jpg

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本文引用的文献

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Quantifying the economic cost of antibiotic resistance and the impact of related interventions: rapid methodological review, conceptual framework and recommendations for future studies.量化抗生素耐药性的经济成本及其相关干预措施的影响:快速方法学综述、概念框架和对未来研究的建议。
BMC Med. 2020 Mar 6;18(1):38. doi: 10.1186/s12916-020-1507-2.
2
Investigating the mechanism of impact of the Quality Premium initiative on antibiotic prescribing in primary care practices in England: a study protocol.调查质量溢价计划对英国初级保健实践中抗生素处方影响的机制:研究方案。
BMJ Open. 2019 Sep 3;9(8):e030093. doi: 10.1136/bmjopen-2019-030093.
3
The true cost of antimicrobial resistance.
抗菌药物耐药性的真实代价。
BMJ. 2013 Mar 11;346:f1493. doi: 10.1136/bmj.f1493.