Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes 2227, São Paulo, 05508-000, Brazil.
Department of Dentistry and Dental Materials, School of Dentistry, Federal University of Minas Gerais, Rua Prof. Moacir Gomes de Freitas, 688, Belo Horizonte, Minas Gerais, Brazil.
Clin Oral Investig. 2022 Dec;26(12):6985-6993. doi: 10.1007/s00784-022-04652-1. Epub 2022 Jul 25.
This randomized controlled trial aimed to evaluate different protocols for dentin hypersensitivity treatment with low-power lasers and desensitizing agents, and the association between low-power lasers and desensitizing agents.
Fifty-four patients (303 teeth) were randomly allocated to three groups: G1, 3% nitrate potassium gel, UltraEZ (n = 17); G2, photobiomodulation therapy (PBM) with a low-level infrared laser (n = 17), 100 mW, spot size of 0.028 cm, and dose of 1 J per point; and G3, nitrate potassium + PBM (n = 20). Treatments were applied to the buccal cervical region at intervals of 72 h, and all protocols were performed in three sessions. The patients' response to evaporative stimuli was rated using the visual analog scale (VAS). Re-evaluations were performed immediately after each application and 1 week, 1 month, and 3 months after treatment. A two-way repeated measures test and Tukey's post hoc test were used for multiple comparisons (α = 5%).
There was a reduction in pain levels at the end of treatment in all groups. There were no significant differences in VAS score changes between the groups immediately after treatment and after the third month, compared to the baseline (p > 0.05).
Under the limitations of this in vivo study, the proposed three-session protocol was effective in reducing dentin hypersensitivity after 3 months, regardless of the desensitization mechanism used. Conservative and long-term protocols are interesting for the control of pain caused by dentin hypersensitivity.
The increase in cervical dentin hypersensitivity prevalence warrants easy-to-apply and long-lasting desensitizing protocols for pain control.
本随机对照试验旨在评估低功率激光和脱敏剂治疗牙本质敏感症的不同方案，以及低功率激光和脱敏剂之间的关联。
将 54 名患者（303 颗牙齿）随机分为三组：G1 组，3%硝酸钾凝胶，UltraEZ（n=17）；G2 组，低水平红外激光光生物调节疗法（PBM）（n=17），100 mW，光斑大小为 0.028 cm，剂量为 1 J 点；G3 组，硝酸钾+PBM（n=20）。治疗间隔为 72 h，在颊侧颈区应用治疗，所有方案均进行 3 次治疗。使用视觉模拟量表（VAS）评估患者对蒸发刺激的反应。每次治疗后立即、治疗后 1 周、1 个月和 3 个月进行重新评估。采用双向重复测量检验和 Tukey 事后检验进行多重比较（α=5%）。
所有组在治疗结束时疼痛水平均降低。与基线相比，治疗后即刻和第 3 个月时，各组 VAS 评分变化无显著差异（p>0.05）。
在本体内研究的限制条件下，所提出的 3 次治疗方案在 3 个月后可有效减轻牙本质敏感症，无论使用何种脱敏机制。保守且长期的方案对于控制牙本质敏感症引起的疼痛很有趣。
颈牙本质敏感症的患病率增加，需要易于应用且持久的脱敏方案来控制疼痛。
