The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China; Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China; Department of Neurology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Neuroimage Clin. 2022;35:103117. doi: 10.1016/j.nicl.2022.103117. Epub 2022 Jul 18.
To investigate the value of diffusion weighted imaging (DWI) in predicting the clinical progression of perforator artery cerebral infarction.
The magnetic resonance imaging (MRI) data of patients with perforator artery cerebral infarction hospitalized in our hospital from October 2015 to February 2022 were analyzed retrospectively. Then we compared the differences of apparent diffusion coefficient (ADC) value, maximal size, location of cerebral infarction, clinical data and treatment plan between the two groups.
A total of 81 patients with perforating artery cerebral infarction were included, with 33 patients in the progressive cerebral infarction (PCI) group and 48 patients in the non-progressive cerebral infarction (NPCI) group. The ADC value in the progressive group was lower than that in the non-progressive group (P < 0.001), and ADC value was an independent factor influencing the clinical progression (OR = 0.974, 95 %CI = 0.960-0.989, P = 0.001); The average area of cerebral infarction in the progressive group was larger than that in the non-progressive group (P = 0.004). There was no difference between the two groups (P > 0.05) in terms of clinical data and treatment plan.
The ADC value and maximal size of infarction were correlated with the clinical Progression. ADC value was an independent factor influencing the clinical progression of perforating artery cerebral infarction, which could be used for the prediction of clinical progress and provide guidance for the development of individualized treatment.
探讨弥散加权成像（DWI）在预测穿支动脉脑梗死临床进展中的价值。
回顾性分析 2015 年 10 月至 2022 年 2 月我院收治的穿支动脉脑梗死患者的磁共振成像（MRI）资料。比较两组患者的表观弥散系数（ADC）值、最大面积、脑梗死部位、临床资料及治疗方案的差异。
共纳入 81 例穿支动脉脑梗死患者，其中进展性脑梗死（PCI）组 33 例，非进展性脑梗死（NPCI）组 48 例。进展组 ADC 值低于非进展组（P<0.001），ADC 值是影响临床进展的独立因素（OR=0.974，95%CI=0.960-0.989，P=0.001）；进展组脑梗死平均面积大于非进展组（P=0.004）。两组患者的临床资料及治疗方案比较，差异无统计学意义（P>0.05）。
ADC 值和梗死最大面积与临床进展相关。ADC 值是影响穿支动脉脑梗死临床进展的独立因素，可用于预测临床进展，为制定个体化治疗方案提供指导。
Zotero 插件
