血清白蛋白和铁蛋白水平：50岁以上急性髓系白血病预后的实用指标？
Serum albumin and ferritin levels: a practical indicator of prognosis in acute myeloid leukemia over 50 years of age?
作者信息
Yokus Osman, Sunger Erdem, Cinli Tahir Alper, Goze Hasan, Serin Istemi
机构信息
University of Health Sciences, Istanbul Training and Research Hospital, Department of Hematology Istanbul, Turkey.
University of Health Sciences, Bagcilar Training and Research Hospital, Department of Internal Medicine Istanbul, Turkey.
出版信息
Am J Blood Res. 2022 Jun 20;12(3):97-104. eCollection 2022.
Abstract
BACKGROUND
Low albumin and high ferritin levels have negative effects on survival in acute myeloid leukemia (AML). In this study, the aim is to determine the role of these factors on survival in patients over 50 years of age with AML.
METHODS
Eighty patients followed up between January 2014 and July 2019 were included in the study. Patients were categorised into three subgroups: The favorable, intermediate and high-risk groups.
RESULTS
The overall survival of the favorable group was found to be longer in a statistically significant way.
CONCLUSION
In this study, it has been shown that serum albumin and ferritin values are useful and simple laboratory values to show prognosis in AML over 50 years of age.
摘要
背景
低白蛋白和高铁蛋白水平对急性髓系白血病（AML）患者的生存有负面影响。本研究旨在确定这些因素对50岁以上AML患者生存的作用。
方法
本研究纳入了2014年1月至2019年7月期间随访的80例患者。患者被分为三个亚组：预后良好组、中等风险组和高风险组。
结果
发现预后良好组的总生存期在统计学上显著更长。
结论
本研究表明，血清白蛋白和铁蛋白值是显示50岁以上AML患者预后的有用且简单的实验室指标。
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