New method of diagnosing neurogenic dysfunction of bladder in candidates for urinary undiversion. Denervation supersensitivity of urethra to alpha-agonist.

Testing for denervation supersensitivity response of the urethra to alpha-agonist as a means of excluding neurogenic vesical dysfunction prior to planning undiversion is discussed in a case report. The method is specifically applicable to the bladder that has shrunk from disuse or fibrosis and therefore is not amenable to conventional bladder function studies.