A new alkaloid and two organic acids from L. and their bioactivities.

A new alkaloid, identified as 1-benzyl-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6,7-diol, named oleraisoquinoline (), and five organic acids and two esters, identified as 5-(hydroxymethyl)furan-2-carboxylic acid (), 1-pyrrole-2,5-dicarboxylic acid (), (7,10)-octadeca-7,10-dienoic acid (), (10,13)-octadeca-10,13-dienoic acid (), (7,10)-hexadeca-7,10-dienoic acid (), methyl tridecanoate () and methyl (9,12)-octadeca-9,12-dienoate (), were isolated from L., among which compounds and ‒ were isolated for the first time. Moreover, the anti-inflammatory activities of compounds ‒ were studied, especially, compound presented good inhibitory effects on the production of inflammatory factors IL-1 and TNF-.