食物对苄氟噻嗪生物利用度的影响。
Effect of food on the bioavailability of bendroflumethiazide.
作者信息
Beermann B, Groschinsky-Grind M, Lindström B
出版信息
Acta Med Scand. 1978;204(4):291-3. doi: 10.1111/j.0954-6820.1978.tb08441.x.
Abstract
Bendroflumethiazide (BFT), 10 mg, was given orally to eight subjects after fasting overnight and together with a meal. Concentrations of the diuretic in plasma and urine were determined by GLC. As judged by AUC and urinary recovery of BFT, the bioavailability of the diuretic was not influenced by concomitant intake of a meal.
摘要
对8名受试者在隔夜禁食后及进食时口服给予10毫克苄氟噻嗪（BFT）。通过气相色谱法测定血浆和尿液中该利尿剂的浓度。根据BFT的曲线下面积（AUC）和尿回收率判断，进餐时同时服用并未影响该利尿剂的生物利用度。
Zotero 插件