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日本表达 3 型肺炎球菌荚膜的侵袭性口腔链球菌。

Invasive Streptococcus oralis Expressing Serotype 3 Pneumococcal Capsule, Japan.

出版信息

Emerg Infect Dis. 2022 Aug;28(8):1720-1722. doi: 10.3201/eid2808.212176.

DOI:10.3201/eid2808.212176
PMID:35876607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9328907/
Abstract

We report 2 adult cases of invasive disease in Japan caused by Streptococcus oralis that expressed the serotype 3 pneumococcal capsule and formed mucoid colonies. Whole-genome sequencing revealed that the identical serotype 3 pneumococcal capsule locus and hyl fragment were recombined into the genomes of 2 distinct S. oralis strains.

摘要

我们报告了 2 例在日本发生的侵袭性疾病的成年病例，这些病例由表达 3 型肺炎球菌荚膜血清型且形成粘液样菌落的口腔链球菌引起。全基因组测序显示，相同的 3 型肺炎球菌荚膜基因座和 hyl 片段被重组到 2 个不同的口腔链球菌菌株的基因组中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7adc/9328907/fbf2cddfac1c/21-2176-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7adc/9328907/fbf2cddfac1c/21-2176-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7adc/9328907/fbf2cddfac1c/21-2176-F.jpg

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本文引用的文献

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Intern Med. 2021 Mar 1;60(5):789-793. doi: 10.2169/internalmedicine.5628-20. Epub 2020 Sep 30.
2
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mBio. 2020 May 19;11(3):e00937-20. doi: 10.1128/mBio.00937-20.
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Pneumococci Can Become Virulent by Acquiring a New Capsule From Oral Streptococci.
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Complete Genome Sequences of Streptococcus pneumoniae Strains HU-OH (Serotype 3, Sequence Type 183 [ST183]), NU83127 (Serotype 4, ST246), and ATCC 49619 (Serotype 19F, ST1203).肺炎链球菌菌株HU-OH（血清型3，序列型183 [ST183]）、NU83127（血清型4，ST246）和ATCC 49619（血清型19F，ST1203）的全基因组序列
Microbiol Resour Announc. 2019 Feb 28;8(9). doi: 10.1128/MRA.01504-18. eCollection 2019 Feb.
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