Scolaro Alessandra, Khijmatgar Shahnawaz, Rai Pooja Mali, Falsarone Francesca, Alicchio Francesca, Mosca Arianna, Greco Christian, Del Fabbro Massimo, Tartaglia Gianluca Martino
Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Bioengineering (Basel). 2022 Jun 22;9(7):269. doi: 10.3390/bioengineering9070269.
The aim of this review was to answer the following PICO question: "Do TMJ kinematic parameters (intervention and comparison) show efficacy for assessment of mandibular function (Outcome) both in asymptomatic and TMD subjects? (Population)". PubMed, Scopus, Web of Science, Embase, Central databases were searched. The inclusion criteria were (1) performed on human, (2) English only, (3) on healthy, symptomatic or surgically altered TMJ, (4) measured dynamic kinematics of mandible or TMJ (5) with six degrees of freedom. To assess the Risk of Bias, the Joanna Briggs Institute tool for non-randomised clinical studies was employed. A pairwise meta-analysis was carried out using STATA v.17.0 (Stata). The heterogeneity was estimated using the Q value and the inconsistency index. Ninety-two articles were included in qualitative synthesis, nine studies in quantitative synthesis. The condylar inclination was significantly increased in female (effect size 0.03°, 95% CI: -0.06, 0.12, = 0.00). Maximum mouth opening (MMO) was increased significantly in female population in comparison with males (effect size 0.65 millimetres (0.36, 1.66). Incisor displacement at MMO showed higher values for control groups compared with TMD subjects (overall effect size 0.16 millimetres (-0.37, 0.69). Evidence is still needed, considering the great variety of devices and parameters used for arthrokinematics. The present study suggests standardising outcomes, design, and population of the future studies in order to obtain more reliable and repeatable values.
本综述的目的是回答以下PICO问题:“颞下颌关节运动学参数(干预和对照)在无症状和颞下颌关节紊乱症(TMD)受试者中,对评估下颌功能(结果)是否有效?(人群)”。检索了PubMed、Scopus、Web of Science、Embase、Central数据库。纳入标准为:(1)针对人类进行;(2)仅为英文;(3)针对健康、有症状或手术改变的颞下颌关节;(4)测量下颌骨或颞下颌关节的动态运动学;(5)具有六个自由度。为评估偏倚风险,采用了乔安娜·布里格斯研究所非随机临床研究工具。使用STATA v.17.0(Stata)进行成对荟萃分析。使用Q值和不一致指数估计异质性。92篇文章纳入定性综合分析,9项研究纳入定量综合分析。女性的髁突倾斜度显著增加(效应量0.03°,95%置信区间:-0.06,0.12,P = 0.00)。与男性相比,女性人群的最大开口度(MMO)显著增加(效应量0.65毫米(0.36,1.66))。与TMD受试者相比,对照组在MMO时的切牙位移值更高(总体效应量0.16毫米(-0.37,0.69))。考虑到用于关节运动学的设备和参数种类繁多,仍需要更多证据。本研究建议对未来研究的结果、设计和人群进行标准化,以获得更可靠和可重复的值。