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15岁以下儿童的结核病死亡率:2010 - 2018年哥伦比亚的流行病学情况

Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010-2018.

作者信息

Plata-Casas Laura, González-Támara Leandro, Cala-Vitery Favio

机构信息

Doctorate in Policy Modeling and Public Management, Faculty of Natural Sciences and Engineering, University Jorge Tadeo Lozano, Bogota 111711, Colombia.

出版信息

Trop Med Infect Dis. 2022 Jun 25;7(7):117. doi: 10.3390/tropicalmed7070117.

Abstract

Pediatric tuberculosis is a serious infectious disease and a hidden global epidemic. The objective of this study was to describe the epidemiological situation of tuberculosis mortality in children under 15 years of age in Colombia in the period 2010-2018. A longitudinal descriptive study was conducted. The variables sex, age groups, and origin were studied. This study had 260 cases for analysis and was carried out in three phases. The first phase was the determination of the sociodemographic and clinical characteristics. The second phase was the construction of indicators by territorial entities. The third phase was stratification into four epidemiological situations according to the mortality rate and years of life lost. The median age was 7 years (range 0-14), 66.5% of cases were pulmonary tuberculosis (97.7% without bacteriological confirmation), 14.3781 years of life lost were recorded (95% CI: 142.811-168.333), and in children under 10-14 years, the loss was 110,057. Amazonas had the highest adjusted YLL rate (3979.7). In total, 36.4% of the territories had a high mortality, and 30.3% adjusted to the situation designated as 1. This is the first study that has used composite indicators to address the problem of premature mortality from childhood tuberculosis in Colombia. Our results allow us to specify that this disease remains a challenge for public health. It requires models of care and differential strategies by region. It also requires ensuring opportunities in diagnosis with sensitive methods, as well as intersectoral work for the optimal approach.

摘要

儿童结核病是一种严重的传染病,也是一场隐匿的全球流行病。本研究的目的是描述2010 - 2018年期间哥伦比亚15岁以下儿童结核病死亡率的流行病学情况。开展了一项纵向描述性研究。研究了性别、年龄组和出生地等变量。本研究有260例病例用于分析,分三个阶段进行。第一阶段是确定社会人口统计学和临床特征。第二阶段是按地区实体构建指标。第三阶段是根据死亡率和寿命损失年数分为四种流行病学情况。中位年龄为7岁(范围0 - 14岁),66.5%的病例为肺结核(97.7%未经细菌学确诊),记录的寿命损失年数为14.3781年(95%置信区间:142.811 - 168.333),10 - 14岁儿童的寿命损失为110,057年。亚马孙地区调整后的寿命损失率最高(3979.7)。总体而言,36.4%的地区死亡率较高,30.3%符合指定为1的情况。这是哥伦比亚第一项使用综合指标来解决儿童结核病过早死亡问题的研究。我们的结果使我们能够明确,这种疾病仍然是公共卫生面临的一项挑战。它需要护理模式和按地区制定的差异化策略。它还需要确保采用敏感方法进行诊断的机会,以及开展部门间合作以实现最佳应对。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/275d/9319292/19e07cdc9415/tropicalmed-07-00117-g0A1.jpg

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