Department of Cardiology, Gebze Fatih State Hospital, Gebze, Kocaeli, Turkey.
Am J Med Sci. 2022 Dec;364(6):729-734. doi: 10.1016/j.amjms.2022.06.028. Epub 2022 Jul 22.
The relationship between small pericardial effusion (SPE) and outcomes has not been well studied in patients with heart failure. Therefore, we aimed to investigate the prevalence and importance of SPE in acute heart failure (AHF).
A total of 398 hospitalized patients with AHF were retrospectively reviewed. Patients' baseline demographic, clinical, echocardiographic, and laboratory characteristics were noted. SPE was defined as the presence of a pericardial effusion <10 mm. The primary outcome was one-year mortality.
SPE was noted in 54 (13.6%) of the patients. Mortality at one year was greater for patients with a small effusion compared with those without SPE (44.4 vs. 11.4%, respectively; p < 0.001), and the one-year mortality rate for the whole group was 15.8%. Age (HR = 1.12, 95% CI 1.054-1.854, p = 0.024), N-terminal pro-B-type natriuretic peptide >4800 pg/ml (HR = 1.628, 95% CI 01.102-4.805, p = 0.001), left ventricular ejection fraction <30% (HR = 1.878, 95% CI 1.154-4.524, p = 0.001), and presence of SPE (HR = 1.567, 95% CI 1.122-2.991, p = 0.005) were independent predictors of one-year mortality on multivariate analysis.
The presence of SPE on admission was an independent predictor of one-year mortality in AHF.
在心力衰竭患者中，小量心包积液（SPE）与结局之间的关系尚未得到很好的研究。因此，我们旨在探讨急性心力衰竭（AHF）中 SPE 的患病率和重要性。
回顾性分析了 398 例住院 AHF 患者。记录了患者的基线人口统计学、临床、超声心动图和实验室特征。SPE 定义为存在<10mm 的心包积液。主要结局为一年死亡率。
54 例（13.6%）患者存在 SPE。与无 SPE 患者相比，小量心包积液患者一年死亡率更高（分别为 44.4%和 11.4%；p<0.001），且整个研究组一年死亡率为 15.8%。年龄（HR=1.12，95%CI 1.054-1.854，p=0.024）、N 末端脑钠肽前体>4800pg/ml（HR=1.628，95%CI 01.102-4.805，p=0.001）、左心室射血分数<30%（HR=1.878，95%CI 1.154-4.524，p=0.001）和 SPE 存在（HR=1.567，95%CI 1.122-2.991，p=0.005）是多变量分析中一年死亡率的独立预测因素。
入院时 SPE 的存在是 AHF 一年死亡率的独立预测因素。
