Sahel J, Flament J, Buchheit F, Bronner A
Ophthalmologica. 1986;193(4):219-24. doi: 10.1159/000309713.
Two anatomo-clinical cases of neuro-ophthalmic sarcoidosis are reported where recognition of systemic involvement was delayed because unusual and quite isolate visual symptoms were present. The first patient had granulomas involving the intracranial optic nerve, presenting as optic nerve glioma. The second case presented as a chiasmal syndrome sharing unusual perimetric evolution. This binasal hemianopsia was probably the consequence of pre-chiasmal circulatory changes. Neuro-ophthalmic sarcoidosis should be included in the differential diagnosis of any involvement of the anterior visual pathways since these localizations are not as rare as was formerly thought. Improved awareness of this condition is a result of better neurodiagnostic studies by computed tomography which was not accurate enough a few years ago.
报告了两例神经眼科结节病的解剖临床病例,由于出现了不寻常且较为孤立的视觉症状,全身性受累的识别被延迟。首例患者颅内视神经有肉芽肿,表现为视神经胶质瘤。第二例表现为交叉综合征,视野变化异常。这种双鼻侧偏盲可能是视交叉前循环改变的结果。神经眼科结节病应纳入任何前部视觉通路受累的鉴别诊断,因为这些定位并不像以前认为的那样罕见。对这种疾病认识的提高得益于计算机断层扫描等神经诊断研究的改进,而几年前这种检查还不够准确。