Lustgarten J S, Mindel J S, Yablonski M E, Friedman A H
J Clin Neuroophthalmol. 1983 Mar;3(1):13-8.
A 32-year old diabetic female had unilateral reduced vision (20/30) in an eye having the ophthalmoscopic appearance of papillophlebitis of the optic nerve head. After an apparently benign course, with recovery, the optic disc became edematous again and a central retinal vein occlusion blinded the eye. Thereafter, an avascular bilobed mass progressively protruded from the optic nerve head. Computerized tomography demonstrated uniform thickening of the optic nerve from the globe through the optic canal. The radiographic appearance was consistent with an optic nerve glioma or meningioma. Spinal fluid, chest x-ray, and serum angiotensin converting enzyme activity were normal. Tuberculin skin test was positive. Optic nerve biopsy demonstrated a noncaseating granuloma and a subsequent Kveim test was positive. Isolated optic nerve sarcoidosis may exist without other systemic manifestations. The appearance on computerized tomography may be similar to that of an optic nerve glioma or meningioma.
一名32岁的糖尿病女性，一只眼睛出现单侧视力下降（20/30），眼底镜检查显示视神经乳头有视乳头静脉炎的表现。在经历了一段看似良性的病程并恢复后，视盘再次水肿，随后视网膜中央静脉阻塞导致该眼失明。此后，一个无血管的双叶状肿物从视神经乳头逐渐突出。计算机断层扫描显示从眼球到视神经管的视神经均匀增厚。影像学表现与视神经胶质瘤或脑膜瘤一致。脑脊液、胸部X线和血清血管紧张素转换酶活性均正常。结核菌素皮肤试验呈阳性。视神经活检显示为非干酪样肉芽肿，随后的Kveim试验呈阳性。孤立性视神经结节病可能在没有其他全身表现的情况下存在。计算机断层扫描的表现可能与视神经胶质瘤或脑膜瘤相似。
