Medical Information Center, Kyushu University Hospital, Fukuoka 812-8582, Japan.
Int J Environ Res Public Health. 2022 Apr 30;19(9):5483. doi: 10.3390/ijerph19095483.
This study aimed to show geographical differences in esophageal cancer mortality in Japan and reveal an association of esophageal cancer mortality with municipal socioeconomic deprivation level. Esophageal cancer mortality data in the Vital Statistics from 2013 to 2017 for each municipality and corresponding population data were analyzed. The deprivation level was derived from the municipal socioeconomic variables by principal component analysis. Municipalities were classified into five quintiles based on the deprivation level, and an association between the level and esophageal cancer mortality was evaluated using a Bayesian spatial model. As a result of regression analysis, the relative risk of esophageal cancer mortality tended to become larger as the deprivation level increased irrespective of sex, and the relative risk of esophageal cancer mortality was significantly higher in quintile 5 (most deprived) than quintile 1 (least deprived) among men and women. These results suggest that the deprivation level increases the risk of esophageal cancer mortality in Japan.
本研究旨在展示日本食管癌死亡率的地域差异，并揭示食管癌死亡率与市县级社会经济贫困程度之间的关联。分析了 2013 年至 2017 年《生命统计》中每个市县级的食管癌死亡率数据和相应的人口数据。通过主成分分析，从市级社会经济变量中得出贫困程度。根据贫困程度将市县级分为五组，并使用贝叶斯空间模型评估水平与食管癌死亡率之间的关系。回归分析结果表明，无论性别如何，食管癌死亡率的相对风险随着贫困程度的增加而增大，男性和女性中，第 5 组（最贫困）的食管癌死亡率的相对风险显著高于第 1 组（最不贫困）。这些结果表明，贫困程度的增加增加了日本食管癌死亡率的风险。
