Department of Pediatrics, 416649Aster Medcity, Kochi, Kerala, India.
Department of Pediatrics, 75619Baby Memorial Hospital, Calicut, Kerala, India.
Trop Doct. 2022 Oct;52(4):553-555. doi: 10.1177/00494755221097046. Epub 2022 Jul 25.
Primary Amoebic meningoencephalitis is a rare and fatal neuro-infection caused by free-living fresh-water amoeba . It is a ubiquitous organism and the infection occurs usually via contact with warm water-bodies. The clinical presentation is often indistinguishable from acute bacterial meningitis and the diagnosis can be made by CSF wet smear examination if there is a high index of suspicion. The disease progresses rapidly compared to pyogenic meningitis and usually has a fatal outcome. Reports of two confirmed cases of primary amoebic meningoencephalitis in children from different centres in Kerala state of India are presented here. In spite of early diagnosis and treatment, both these patients demised. Primary amoebic meningoencephalitis should be considered in the differential diagnosis of acute meningitis, especially in patients with recent freshwater exposure. Implementation of chlorination of pools of water bodies, especially if re-opened for recreational purpose after prolonged periods of non-use, needs vigorous implementation.
原发性阿米巴脑膜脑炎是一种罕见且致命的神经感染，由自由生活的淡水阿米巴引起。它是一种无处不在的生物体，感染通常通过接触温水体发生。临床表现通常与急性细菌性脑膜炎无法区分，如果高度怀疑，可通过 CSF 湿抹片检查进行诊断。与化脓性脑膜炎相比，该病进展迅速，通常导致致命后果。本文介绍了来自印度喀拉拉邦不同中心的两名确诊儿童原发性阿米巴脑膜脑炎病例。尽管进行了早期诊断和治疗，但这两名患者都死亡了。原发性阿米巴脑膜脑炎应在急性脑膜炎的鉴别诊断中考虑，特别是在近期接触淡水的患者中。应大力实施对水体池的氯化处理，特别是在长时间停用后重新开放用于娱乐目的的水体池。
