使用甘菊茶浸剂减轻头颈部癌症患者放疗引起的干性脱皮。
Use of Chamomile Infusion to Mitigate Radiotherapy-Induced Dry Desquamation in Head and Neck Cancer Patients.
机构信息
Interdisciplinary Laboratory of Research Applied to Clinical Practice in Oncology, Faculty of Health Sciences, University of Brasília, Brasília, Brazil.
Laboratory of Oral Histopathology, Faculty of Health Sciences, University of Brasília, Brasília, Brazil.
出版信息
Integr Cancer Ther. 2022 Jan-Dec;21:15347354221105491. doi: 10.1177/15347354221105491.
PURPOSE
To evaluate the effect of using a compress with infusion in the regression of dry desquamation and in the prevention of moist desquamation in head and neck cancer patients undergoing radiotherapy.
METHODS
A prospective intervention study was carried out from May 2019 to May 2021. In total, 43 participants were included, who were instructed to apply the compress with the infusion 3 times a day, after occurrence of dry desquamation. Skin evaluation took place daily from initiation of the intervention up to the end of radiotherapy.
RESULTS
All the participants presented dry desquamation regression, where 65.1% (95% CI 50.1-78.1) had total regression until the end of radiotherapy, with a mean of 9 days of regression. Only 34.9% (95% CI 21.8-49.9) of the participants developed moist desquamation by the end of the radiotherapy sessions, with a mean accumulated dose of ionizing radiation of 50.9 Gy.
CONCLUSION
This study highlighted the potential clinical benefits of using in the regression of dry desquamation and in the prevention of moist desquamation.
目的
评估在头颈癌患者放疗中使用含浸敷贴治疗干性脱皮和预防湿性脱皮的效果。
方法
本前瞻性干预研究于 2019 年 5 月至 2021 年 5 月进行。共纳入 43 名参与者，在发生干性脱皮后，指导他们每天使用含浸敷贴 3 次。从干预开始到放疗结束，每天进行皮肤评估。
结果
所有参与者的干性脱皮均有消退，其中 65.1%（95%CI 50.1-78.1）在放疗结束前完全消退，平均消退时间为 9 天。仅有 34.9%（95%CI 21.8-49.9）的参与者在放疗结束时出现湿性脱皮，累积电离辐射剂量平均为 50.9Gy。
结论
本研究强调了使用含浸敷贴治疗干性脱皮和预防湿性脱皮的潜在临床益处。
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