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单层软骨膜剥离对兔耳软骨生长的影响。

The effects of unilamellar perichondrial dissection on the growth of rabbit ear cartilage.

作者信息

Wellisz T Z, Cutting C B, McCarthy J G

出版信息

Plast Reconstr Surg. 1987 Jun;79(6):935-40. doi: 10.1097/00006534-198706000-00014.

Abstract

The effects of elevation of the perichondrium from a surface of growing ear cartilage were investigated in immature rabbits. Eight 21-day-old rabbits completed the study in which perichondrium was elevated from one cartilaginous surface of one ear and the nonoperated ear served as a control. By maturity, both ears had developed symmetrically and no statistically significant difference could be demonstrated in length and surface area. Although several ears demonstrated subtle shape changes, the overall growth and development of the surgically manipulated ear cartilages did not appear to be affected. These findings appear to contradict a widely held view that perichondrial dissection of developing cartilage has a high potential for subsequent growth disturbances. The corollary has been that cartilage manipulation, such as that required in the surgical repair of the cleft lip nose deformity, should be delayed until the growth of cartilage is complete. These data would support the findings of long-term clinical studies which demonstrate the efficacy of early limited perichondrial dissection in the correction of the cleft lip nose deformity.

摘要

在未成熟的兔子身上研究了从生长中的耳软骨表面掀起软骨膜的影响。八只21日龄的兔子完成了该研究,其中从一只耳朵的一个软骨表面掀起软骨膜,未手术的耳朵作为对照。到成熟时,两只耳朵对称发育,在长度和表面积上没有显示出统计学上的显著差异。尽管几只耳朵表现出细微的形状变化,但手术操作的耳软骨的整体生长和发育似乎并未受到影响。这些发现似乎与一种广泛持有的观点相矛盾,即对发育中的软骨进行软骨膜剥离有很高的后续生长紊乱可能性。由此得出的推论是,软骨操作,如唇裂鼻畸形手术修复中所需的操作,应推迟到软骨生长完成后进行。这些数据将支持长期临床研究的结果,这些研究证明了早期有限的软骨膜剥离在矫正唇裂鼻畸形中的有效性。

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