Amouyal Gregory, Tournier Louis, de Margerie-Mellon Constance, Bouda Damien, Pachev Atanas, Assouline Jessica, de Bazelaire Cédric, Marques Florent, Le Strat Solenne, Desgrandchamps François, De Kerviler Eric
Hôpital Privé Geoffroy Saint-Hilaire-Ramsay Santé, 75005 Paris, France.
Radiology Department, Hôpital Saint-Louis, 75010 Paris, France.
J Pers Med. 2022 Jul 14;12(7):1138. doi: 10.3390/jpm12071138.
to evaluate the safety and feasibility of a shorter time to hemostasis applied to outpatient transradial (TR) Prostatic Artery Embolization (PAE).
a retrospective bi-institutional study was conducted between July 2018 and April 2022 on 300 patients treated by outpatient TR PAE. Indications included lower urinary tract symptoms, acute urinary retention, and hematuria. Mean patient height was 176 ± 6.3 (158-192) cm. The primary endpoint was safety of a 45 min deflation protocol for hemostasis. The secondary endpoint was the feasibility of PAE using TR access.
technical success was 98.7% (296/300). There was one failure due to patient height. Mean DAP/fluoroscopy times were 16,225 ± 12,126.3 (2959-81,608) μGy·m/35 ± 14.7 (11-97) min, and mean time to discharge was 80 ± 6 (75-90) min. All access site and embolization-related adverse events were minor. Mild hematoma occurred in 10% (30/300), radial artery occlusion (RAO) in 10/300 (3.3%) cases, and history of smoking was a predictor for RAO. There was no major event.
the safety of TR PAE using a 45 min time to hemostasis was confirmed, and TR PAE is feasible in most cases. Radial artery occlusion was still observed and may be favored by smoking.
评估缩短止血时间应用于门诊经桡动脉（TR）前列腺动脉栓塞术（PAE）的安全性和可行性。
2018年7月至2022年4月间进行了一项双机构回顾性研究，纳入300例行门诊TR PAE治疗的患者。适应证包括下尿路症状、急性尿潴留和血尿。患者平均身高为176±6.3（158 - 192）cm。主要终点是采用45分钟放气方案止血的安全性。次要终点是经TR途径行PAE的可行性。
技术成功率为98.7%（296/300）。有1例因患者身高导致手术失败。平均剂量面积乘积（DAP）/透视时间为16,225±12,126.3（2959 - 81,608）μGy·m/35±14.7（11 - 97）分钟，平均出院时间为80±6（75 - 90）分钟。所有穿刺部位及与栓塞相关的不良事件均较轻微。10%（30/300）的患者出现轻度血肿，10/300（3.3%）的病例发生桡动脉闭塞（RAO），吸烟史是RAO的一个预测因素。无重大事件发生。
证实了采用45分钟止血时间的TR PAE的安全性，且TR PAE在大多数情况下是可行的。仍观察到桡动脉闭塞情况，吸烟可能是其诱因。
