Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, Taiwan.
Department of Ophthalmology and Visual Science, Tzu Chi University, Hualien 970, Taiwan.
Medicina (Kaunas). 2022 Jun 22;58(7):840. doi: 10.3390/medicina58070840.
Apocrine hidrocystomas are benign cystic tumors resulting from apocrine sweat glands' proliferation. They typically present as solitary, slow-growing nodules at the head and neck, especially in the periorbital cutaneous region. We present a case of periorbital apocrine hidrocystoma in a 22-year-old woman that was treated as chalazion previously. Besides the hallmark histopathological findings of apocrine hidrocystoma, IgG4 plasma cell infiltration of the cystic wall was also found. The ratio of IgG4-to-IgG-positive plasma cells was high, whereas serum IgG4 was within the standard limit. This is, to date, the only probable IgG4-related ophthalmic disease associated with apocrine hidrocystoma.
顶泌汗腺性汗管囊瘤是由顶泌汗腺增殖引起的良性囊性肿瘤。它们通常表现为头颈部的单发、生长缓慢的结节，尤其是眶周皮肤区域。我们报告了一例 22 岁女性的眶周顶泌汗腺性汗管囊瘤，该患者此前曾被误诊为霰粒肿。除了顶泌汗腺性汗管囊瘤的标志性组织病理学发现外，还发现囊壁内 IgG4 浆细胞浸润。IgG4 阳性浆细胞与 IgG 阳性浆细胞的比值较高，而血清 IgG4 在正常范围内。这是迄今为止唯一可能与顶泌汗腺性汗管囊瘤相关的 IgG4 相关眼病。
