School of Nursing, Capital Medical University, 10 Xitoutiao Road, Fengtai District, Beijing 100069, China.
Department of Gynaecology and Obstetrics, Peking University Third Hospital, 49 Huayuan Beilu Road, Haidian District, Beijing 100191, China.
Nutrients. 2022 Jul 7;14(14):2799. doi: 10.3390/nu14142799.
Preterm birth is a leading cause of neonatal and child mortality and morbidity worldwide. The aim of this study was to investigate associations between attending a brief antenatal lifestyle education seminar and preterm birth, and whether education timing modifies outcomes. A retrospective cohort study was conducted in a hospital-based antenatal care center in Beijing, China, where a free, 2 h, optional, face-to-face, midwife-led group seminar on healthy lifestyle choices during pregnancy was provided. Among the 3008 eligible women, 1107 (36.8%) attended the seminar during the first trimester, 515 (17.1%) attended during the second trimester or later, and 1386 (46.1%) did not attend. Multiparous women were more likely to not attend or to attend at a later stage. The overall prevalence of preterm birth was 8.7%, but it was higher for women who did not attend the antenatal seminar (11.5%). The risk of preterm birth for first trimester attendees decreased by 53%, and it decreased by 41% for later attendees. Estimates persisted after adjusting pre-existing and gestational covariates. Attending a brief antenatal lifestyle education seminar was associated with lower preterm birth risk, and attending during the first trimester had a better impact than later attendance. The results can inform the development of tailored preterm birth prevention strategies.
早产是全球新生儿和儿童死亡和发病的主要原因。本研究旨在探讨参加简短的产前生活方式教育研讨会与早产之间的关联，以及教育时机是否会改变结局。本研究在中国北京的一家医院产前保健中心进行了一项回顾性队列研究，该中心提供了一个免费的、2 小时的、可选的、面对面的、由助产士主导的小组研讨会，内容是关于孕期健康生活方式的选择。在 3008 名符合条件的女性中，1107 名（36.8%）在孕早期参加了研讨会，515 名（17.1%）在孕中期或后期参加了研讨会，1386 名（46.1%）没有参加。多产妇更有可能不参加或参加较晚的阶段。早产的总体发生率为 8.7%，但未参加产前研讨会的女性更高（11.5%）。参加产前研讨会的女性早产风险降低了 53%，而参加较晚阶段的女性早产风险降低了 41%。调整了预先存在的和妊娠相关的协变量后，估计值仍然存在。参加简短的产前生活方式教育研讨会与降低早产风险相关，而且在孕早期参加比后期参加的效果更好。研究结果可为制定有针对性的早产预防策略提供信息。
