烟曲霉毒素，来自烟曲霉弗里斯的新型霉菌毒素
Fumitoxins, new mycotoxins from Aspergillus fumigatus Fres.
作者信息
Debeaupuis J P, Lafont P
出版信息
Appl Environ Microbiol. 1978 Jul;36(1):8-10. doi: 10.1128/aem.36.1.8-10.1978.
Abstract
Extracts of cultures of Aspergillus fumigatus isolated from silage were lethal to chicken embryos. Using this test and thin-layer chromatography, four UV-absorbing toxins, designated as fumitoxins A, B, C and D, were isolated. Analysis and mass spectrometry of crystallized fumitoxin A, the most abundant in the extract, established its molecular formula to be C31H42O8. Infrared, UV spectroscopy, and chemical reactions suggested that fumitoxin A is a steroid. Fumitoxins appear to be clearly different from the previously described toxins recognized in A. fumigatus.
摘要
从青贮饲料中分离出的烟曲霉培养物提取物对鸡胚具有致死性。利用该检测方法和薄层色谱法，分离出了四种紫外线吸收毒素，分别命名为烟曲霉毒素A、B、C和D。提取物中含量最高的结晶状烟曲霉毒素A经分析和质谱测定，确定其分子式为C31H42O8。红外光谱、紫外光谱及化学反应表明烟曲霉毒素A是一种类固醇。烟曲霉毒素似乎与先前描述的烟曲霉毒素明显不同。
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Ann Inst Pasteur (Paris). 1970 Mar;118(3):340-8.
2
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Mycopathol Mycol Appl. 1974 Nov 29;54(3):291-6. doi: 10.1007/BF02050163.
3
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C R Seances Soc Biol Fil. 1969;163(6):1362-4.
4
[New toxins from Aspergillus fumigatus Fresenius].
C R Acad Hebd Seances Acad Sci D. 1978 Feb 6;286(5):431-4.
5
Mycotoxins produced by Aspergillus fumigatus species isolated from molded silage.从发霉青贮饲料中分离出的烟曲霉属产生的霉菌毒素。
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6
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