Ishiguro N, Oka C, Sato G
Appl Environ Microbiol. 1978 Aug;36(2):217-22. doi: 10.1128/aem.36.2.217-222.1978.
Twenty-seven isolates of citrate-positive variants of Escherichia coli were obtained from domestic pigeons, pigs, cattle, and horses. With the exception of citrate utilization, all isolates closely resembled typical E. coli in their biochemical reactions. These isolates were multiply resistant to antibiotics in in vitro susceptibility tests. Transfer experiments of multiple-drug resistance to the E. coli K-12 strain showed that all citrate-positive isolates from domestic pigeons, pigs, and cattle, resistant to three or more drugs, carried R plasmids showing temperature-sensitive transfer.
从家鸽、猪、牛和马中获得了27株大肠杆菌柠檬酸盐阳性变异株。除柠檬酸盐利用情况外,所有分离株在生化反应方面与典型大肠杆菌极为相似。在体外药敏试验中,这些分离株对多种抗生素具有多重耐药性。对大肠杆菌K-12菌株进行多重耐药性转移实验表明,所有来自家鸽、猪和牛且对三种或更多种药物耐药的柠檬酸盐阳性分离株都携带表现出温度敏感转移特性的R质粒。