Pușcașu Claudia Irina, Rimbaş Mihai, Mateescu Radu Bogdan, Larghi Alberto, Cauni Victor
Gastroenterology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Department of Internal Medicine, Carol Davila University of Medicine, 050474 Bucharest, Romania.
Diagnostics (Basel). 2022 Jul 22;12(8):1779. doi: 10.3390/diagnostics12081779.
Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis.
胰腺囊性病变（PCLs）是一组异质性病变，范围从良性到恶性。近年来，PCLs的患病率有所上升，主要是由于成像技术的进步、对其存在的认识增加以及人口老龄化。对肿瘤性和非肿瘤性囊性病变进行可靠区分对于确保适当的治疗和随访至关重要。尽管传统诊断技术如超声（US）、磁共振成像（MRI）和计算机断层扫描（CT）能够轻松识别这些病变，但评估恶性风险的能力有限。内镜超声（EUS）在识别潜在恶性病变方面优于横断面成像，因为其具有高分辨率和更好的成像特性，并且具有通过细针穿刺抽吸（FNA）进行囊液采样的优势。更复杂的检测，如对抽吸液进行细胞学和组织病理学分析以及生化和分子检测，能够确保准确诊断。
