阴囊磁共振成像在超声检查不确定的睾丸病变术前检查中的诊断价值——一项回顾性多中心分析

The Diagnostic Value of the Added MR Imaging of the Scrotum in the Preoperative Workup of Sonographically Indeterminate Testicular Lesions-A Retrospective Multicenter Analysis.

作者信息

Deininger Susanne, Lusuardi Lukas, Pallauf Maximilian, Hecht Stefan, Forstner Rosemarie, Meissnitzer Matthias, Distler Florian A, Erne Eva, Graf Sebastian, Lenart Sebastian, Putz Juliane, Deininger Christian, Törzsök Peter

机构信息

Department of Urology and Andrology, Paracelsus Medical University, 5020 Salzburg, Austria.

Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.

出版信息

Cancers (Basel). 2022 Jul 23;14(15):3594. doi: 10.3390/cancers14153594.

DOI:10.3390/cancers14153594

PMID:35892855

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9330050/

Abstract

BACKGROUND

The purpose of this study was to retrospectively analyze the diagnostic accuracy of magnetic resonance imaging (MRI) examinations of the scrotum in comparison with standard ultrasound (US) and histopathology.

METHODS

A retrospective multi-center analysis of MRI examinations of the scrotum performed between 06/2008 and 04/2021 was conducted.

RESULTS

A total of = 113 patients were included. A total of 53 histopathologies were available, with 52.8% malignant and 50.9% benign findings. Related to histopathology, imaging was true negative, false negative, false positive, and true positive in 4.1%, 2.1%, 25.0% and 37.5% for standard ultrasound (US) and 9.1%, 1.8%, 25.5% and 43.6% for MRI. Sensitivity, specificity, positive predictive value and negative predictive value were 94.7%, 20.0%, 36.0% and 88.9% for US and 85.7%, 72.8%, 52.1% and 93.7% for MRI, respectively. Benign lesions were significantly smaller than malignant ones in standard US ( = 0.001), histopathology ( = 0.001) and MRI ( = 0.004). The size of malignant tumors did not differ significantly between histopathology and standard US (0.72) and between histopathology and MRI ( = 0.88).

CONCLUSIONS

MRI shows good sensitivity and specificity for the estimation of testicular tumors in this collective. Benign lesions are significantly smaller than malignant ones. Both MRI and US can estimate the size of malignant tumors adequately.

摘要

背景

本研究的目的是回顾性分析阴囊磁共振成像（MRI）检查与标准超声（US）及组织病理学检查相比的诊断准确性。

方法

对2008年6月至2021年4月期间进行的阴囊MRI检查进行回顾性多中心分析。

结果

共纳入113例患者。共有53份组织病理学报告，其中恶性病变占52.8%，良性病变占50.9%。与组织病理学相关，标准超声（US）的成像真阴性、假阴性、假阳性和真阳性率分别为4.1%、2.1%、25.0%和37.5%，MRI的分别为9.1%、1.8%、25.5%和43.6%。US的敏感性、特异性、阳性预测值和阴性预测值分别为94.7%、20.0%、36.0%和88.9%，MRI的分别为85.7%、72.8%、52.1%和93.7%。在标准US（P = 0.001）、组织病理学（P = 0.001）和MRI（P = 0.004）中，良性病变明显小于恶性病变。组织病理学与标准US之间（P = 0.72）以及组织病理学与MRI之间（P = 0.88），恶性肿瘤的大小无显著差异。