Wells Hannah C, Sizeland Katie H, Kirby Nigel, Haverkamp Richard G
School of Food and Advanced Technology, Massey University, Palmerston North 4442, New Zealand.
ANSTO, Lucas Heights, NSW 2234, Australia.
Biology (Basel). 2022 Jul 23;11(8):1096. doi: 10.3390/biology11081096.
Thin, strong scaffold materials are needed for surgical applications. New materials are required, particularly those readily available, such as from non-human sources. Bovine amniotic membrane (antepartum) and equine amniotic membrane (postpartum) were characterized with tear and tensile tests. The structural arrangement of the collagen fibrils was determined by small-angle X-ray scattering, scanning electron microscopy, and ultrasonic imaging. Bovine amnion had a thickness-normalized tear strength of 12.6 (3.8) N/mm, while equine amnion was 14.8 (5.3) N/mm. SAXS analysis of the collagen fibril arrangement yielded an orientation index of 0.587 (0.06) and 0.681 (0.05) for bovine and equine, respectively. This may indicate a relationship between more highly aligned collagen fibrils and greater strength, as seen in other materials. Amnion from bovine or equine sources are strong, thin, elastic materials, although weaker than other collagen tissue materials commonly used, that may find application in surgery as an alternative to material from human donors.
外科手术应用需要薄而坚固的支架材料。需要新型材料，尤其是那些易于获取的材料，比如来自非人类来源的材料。对牛羊膜（产前）和马羊膜（产后）进行了撕裂和拉伸测试。通过小角X射线散射、扫描电子显微镜和超声成像确定了胶原纤维的结构排列。牛羊膜的厚度归一化撕裂强度为12.6（3.8）N/mm，而马羊膜为14.8（5.3）N/mm。对胶原纤维排列的小角X射线散射分析得出，牛和马的取向指数分别为0.587（0.06）和0.681（0.05）。这可能表明，如在其他材料中所见，胶原纤维排列越高度对齐，强度就越大。牛或马来源的羊膜是坚固、薄且有弹性的材料，尽管比常用的其他胶原组织材料弱，但可能作为人类供体材料的替代品用于外科手术。
