Bastianelli Mark, Huang Lucy, Moore Paige, Iqbal Isma Zafar, Woods Charmaine M, Ooi Eng H
Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia.
College of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia.
J Clin Med. 2022 Jul 26;11(15):4329. doi: 10.3390/jcm11154329.
The endoscopic modified Lothrop procedure (EMLP) is a common procedure performed in patients with frontal sinus pathology. While performing this procedure, large segments of bone are exposed, which may lead to the promotion of frontal sinus neo-ostium stenosis. Here we examine the peri-operative differences in time to achieve healing in patients where a mucosal flap is used to cover the exposed bone on one side of the neo-ostium. A randomised pilot study with 12 patients undergoing EMLP surgery participated in this study. Patients were randomised to undergo a mucosal flap on either the left or right side of the neo-ostium. Prior to surgery, patients completed a SNOT-22 and smell identification test. Patients were reviewed until the neo-ostium had healed on both sides. Once healing had occurred, a post-operative SNOT-22 score and smell identification test were recorded. Average time to healing for the frontal sinus neo-ostium was 4.7 vs. 4.2 ( = 0.3) on the flap vs. non-flap side, respectively. There was an average 24.4 point (range: -75 to +9) decrease in SNOT-22 scores post-surgery. The post-operative USPIT score demonstrated an average increase of 6.6 points (range -13 to +27). We did not detect significant differences in peri-operative time toward healing in neo-ostiums where a single flap is utilised. Further studies are needed to determine whether the usage of a single neo-ostium flap affords any benefit over no flap on either ostium. SNOT-22 and UPSIT scores improved post-surgery.
内镜改良Lothrop手术(EMLP)是治疗额窦病变患者的常用手术。在进行该手术时,大片骨组织会暴露在外,这可能会导致额窦新口狭窄。在此,我们研究了在新口一侧使用黏膜瓣覆盖暴露骨组织的患者围手术期愈合时间的差异。一项随机试点研究纳入了12例接受EMLP手术的患者。患者被随机分为在新口左侧或右侧使用黏膜瓣。手术前,患者完成SNOT-22和嗅觉识别测试。对患者进行随访,直至新口两侧均愈合。一旦愈合,记录术后SNOT-22评分和嗅觉识别测试结果。额窦新口的平均愈合时间在使用黏膜瓣侧为4.7天,未使用黏膜瓣侧为4.2天(P = 0.3)。术后SNOT-22评分平均下降24.4分(范围:-75至+9)。术后USPIT评分平均提高6.6分(范围:-13至+27)。我们未发现使用单个黏膜瓣的新口围手术期愈合时间存在显著差异。需要进一步研究以确定使用单个新口黏膜瓣是否比不使用黏膜瓣有任何益处。术后SNOT-22和UPSIT评分有所改善。