Liu Yu, Hawkins Mary, Osman Amna, Zhang Chen
Division of Epidemiology, Department of Public Health Sciences, University of Rochester Medical Center, 256 Crittenden Blvd., Ste. 3305, Rochester, NY 14642, USA.
Nashville Council on AIDS, Resources, Education and Support (CARES), Nashville, TN 37204, USA.
Trop Med Infect Dis. 2022 Jul 26;7(8):146. doi: 10.3390/tropicalmed7080146.
Self-initiated Human Immunodeficiency Virus (HIV) testing after potential sexual exposure to HIV (i.e., exposure-influenced HIV testing) has high utility in detecting individuals with the highest probabilities of HIV seroconversion. We conducted a cross-sectional study among a sample of sexually active, pre/post-exposure prophylaxis (PrEP/PEP)-naïve young men who have sex with men (YMSM) in two US cities to assess the determinants (e.g., demographic, psychosocial, sexual, substance use, and HIV prevention characteristics) of exposure-influenced HIV testing ( vs. ) in their lifetime. Of 261 YMSM, only 26.5% reported seeking exposure-influenced prior to the study. Multivariable analyses showed that younger age, sexual orientation non-disclosure, perceived HIV stigma, internalized homophobia, lower general resilience, and lower social support were associated with a lower likelihood of seeking exposure-influenced HIV testing. YMSM who sought exposure-influenced HIV testing were more likely to use recreational drugs before sex, binge alcohol, and have group sex; while less likely to be aware of PrEP, test for sexually transmitted infections, or use condoms compared to those seeking exposure-influenced HIV testing. Exposure-influenced HIV testing is suboptimal among YMSM with elevated risk for HIV. Our findings provide important implications for designing targeted interventions to promote exposure-influenced HIV testing among high-risk YMSM.
在潜在的性接触感染人类免疫缺陷病毒（HIV）后自行进行HIV检测（即受接触影响的HIV检测），对于检测HIV血清转化可能性最高的个体具有很高的实用性。我们在美国两个城市对一群有性行为、未接受过暴露前/暴露后预防（PrEP/PEP）的男男性行为青年（YMSM）进行了一项横断面研究，以评估其一生中受接触影响的HIV检测（与未进行此类检测相比）的决定因素（如人口统计学、心理社会、性、物质使用和HIV预防特征）。在261名YMSM中，只有26.5%的人报告在研究前寻求过受接触影响的HIV检测。多变量分析表明，年龄较小、未公开性取向、感知到的HIV污名、内化的恐同心理、较低的总体复原力和较低的社会支持与寻求受接触影响的HIV检测的可能性较低有关。寻求受接触影响的HIV检测的YMSM在性行为前更可能使用娱乐性药物、狂饮酒精和进行群交；与未寻求受接触影响的HIV检测的人相比，他们了解PrEP、进行性传播感染检测或使用避孕套的可能性较小。在HIV风险较高的YMSM中，受接触影响的HIV检测情况并不理想。我们的研究结果为设计有针对性的干预措施以促进高危YMSM进行受接触影响的HIV检测提供了重要启示。
