Hoba Sylvia, Fink Gereon R, Zeng Hang, Weidner Ralph
Institute of Neuroscience and Medicine, INM-3, Research Center Jülich, 52425 Jülich, Germany.
Department of Neurology, University Hospital Cologne, Cologne University, 50937 Cologne, Germany.
Vision (Basel). 2022 Jul 1;6(3):41. doi: 10.3390/vision6030041.
Prior knowledge alters perception already on early levels of processing. For instance, judging the display size of an object is affected by its familiar size. Using functional magnetic resonance imaging, we investigated the neural processes involved in resolving ambiguities between familiar object size and physical object size in 33 healthy human subjects. The familiar size was either small or large, and the object was displayed as either small or large. Thus, the size of the displayed object was either congruent or incongruent with its internally stored canonical size representation. Subjects were asked to indicate where the stimuli appeared on the screen as quickly and accurately as possible, thereby ensuring that differential activations cannot be ascribed to explicit object size judgments. Incongruent (relative to congruent) object displays were associated with enhanced activation of the right intraparietal sulcus (IPS). These data are consistent with but extend previous patient studies, which found the right parietal cortex involved in matching visual objects presented atypically to prototypical object representations, suggesting that the right IPS supports view normalization of objects. In a second experiment, using a parametric design, a region-of-interest analysis supported this notion by showing that increases in size mismatch between the displayed size of an object and its familiar viewing size were associated with an increased right IPS activation. We conclude that the right IPS performs view normalization of mismatched information about the internally stored prototypical size and the current viewing size of an object.
已有知识在早期加工阶段就会改变感知。例如，判断一个物体的显示大小会受到其熟悉大小的影响。我们使用功能磁共振成像技术，研究了33名健康人类受试者在解决熟悉物体大小与实际物体大小之间的模糊性时所涉及的神经过程。熟悉大小要么小要么大，物体显示为要么小要么大。因此，显示物体的大小与其内部存储的标准大小表征要么一致要么不一致。要求受试者尽快且准确地指出刺激在屏幕上出现的位置，从而确保差异激活不能归因于明确的物体大小判断。与一致情况相比，不一致的物体显示与右侧顶内沟（IPS）的激活增强有关。这些数据与之前的患者研究一致，但有所扩展，之前的研究发现右侧顶叶皮层参与将非典型呈现的视觉物体与原型物体表征进行匹配，这表明右侧IPS支持物体的视图归一化。在第二个实验中，采用参数设计，感兴趣区域分析支持了这一观点，即物体显示大小与其熟悉观看大小之间的大小不匹配增加与右侧IPS激活增加相关。我们得出结论，右侧IPS对关于物体内部存储的原型大小和当前观看大小的不匹配信息进行视图归一化。
