Research Group "Multidisciplinary Assessment and Intervention in Health Care and Sustainable Lifestyles VIMAS+", Nursing Faculty, University of Valladolid, 47005 Valladolid, Spain.
Department of Surgery and Bariatric Surgery, Real San Jose Hospital, Guadalajara 45040, Mexico.
Nutrients. 2022 Jul 26;14(15):3056. doi: 10.3390/nu14153056.
The aim of this study was to compare the analytical and densitometric changes 2 years after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG). A retrospective study of a prospectively collected database was performed. Morbidly obese patients undergoing RYGB or SG, as primary bariatric procedures, were included. Weight loss; analytical levels of parathormone (PTH), vitamin D, and calcium; and densitometric parameters were investigated. In total, 650 patients were included in the study, and 523 patients (80.5%) underwent RYGB and 127 (19.5%) SG. There were no significant differences in excess weight loss at 24 months between both groups. When comparing preoperative and postoperative values, a significantly greater increase in PTH values was observed in the RYGB group, whereas there were no significant differences in calcium and vitamin D levels. The mean -score values decreased after surgery at all the locations and in both groups. The reduction in the -score was significantly greater in the RYGB group at the femoral trochanter and lumbar spine. A decrease in bone mineral density (BMD) was observed after both techniques. The mean BMD decrease was significantly greater in the femoral trochanter and lumbar spine after RYGB.
本研究旨在比较 Roux-en-Y 胃旁路术（RYGB）和袖状胃切除术（SG）后 2 年的分析和密度测定变化。对前瞻性收集的数据库进行了回顾性研究。纳入接受 RYGB 或 SG 作为原发性减肥手术的病态肥胖患者。研究了减肥效果、甲状旁腺激素（PTH）、维生素 D 和钙的分析水平以及密度测定参数。共纳入 650 例患者，其中 523 例（80.5%）接受 RYGB，127 例（19.5%）接受 SG。两组 24 个月时的超重减轻量无显著差异。与术前值相比，RYGB 组的 PTH 值显著升高，而钙和维生素 D 水平无显著差异。手术后所有部位和两组的 -评分值均降低。RYGB 组在股骨转子和腰椎的 -评分降低幅度显著更大。两种技术后均观察到骨密度（BMD）降低。RYGB 后股骨转子和腰椎的平均 BMD 降低幅度显著更大。
